Abstract Knowledge of the molecular mechanisms on malignant tumors is very critical for the
development of new treatment strategies like molecularly targeted therapies. In last 5 years …

In humans, the adaptive immune system uses the exchange of information between cells to
detect and eliminate foreign or damaged cells; however, the removal of unwanted cells does …

Gastric cancer is resistant to chemotherapy, especially in the later stages. The prevalence of
gastric cancer increases after the age of 40, and its peak is in the 7th decade of life. The …

Rapid development and deployment of engineered nanomaterials, such as amorphous
silica nanoparticles (SiNPs) in various commercial and biomedical applications have raised …

STMN1 belongs to the stathmin gene family, it encodes a cytoplasmic phosphorylated
protein, stathmin1, which is commonly observed in vertebrate cells. STMN1 is a structural …

Objective The aim of the study was to explore the mechanism of excessive apoptosis of
nucleus pulposus cells induced by short hairpin RNA (shRNA) Piezo type mechanosensitive …

Gastric cancer poses a significant health challenge, and exploring innovative therapeutic
strategies is imperative. RNA interference (RNAi) has employed as an important therapeutic …

The gastric cancer (GC) is biologically and genetically heterogeneous with a poorly
understood carcinogenesis at the molecular level. Herein, we studied the effects of …

Background Individualized therapeutic regimen is a recently intensively pursued approach
for targeting diseases, in which the search for biomarkers was considered the first and most …

Objective To observe the mechanism of IGFBP2 knock-down in improving lung fibrosis and
inflammation through STAT3 pathway in rats with severe pneumonia. Materials and Methods …