Erythropoiesis is a complex process that starts in the course of embryo formation and it is
maintained throughout the life of an organism. During the fetal development, erythropoiesis …

ABSTRACT GATA1 is a critical regulator of erythropoiesis. While the mechanisms
underlying the high-level expression of GATA1 in maturing erythroid cells have been studied …

In mammals, hematopoietic homeostasis is maintained by a fine‐tuned balance among the
self‐renewal, proliferation, differentiation and survival of hematopoietic stem cells and their …

Background The hERG potassium channel can modulate the proliferation of the chronic
myelogenous leukemic K562 cells, and its role in the erythroid differentiation of K562 cells …

The phenolic metabolite of benzene, hydroquinone (HQ), has potential risks for
hematological disorders and hematotoxicity in humans. Previous studies have revealed that …

Caveolins (CAVs) are structural proteins of caveolae that function as signaling platforms to
regulate smooth muscle contraction. Loss of CAV protein expression is associated with …

Acute erythroleukemia (AEL) is an infrequent subtype of acute myeloid leukemia (AML) with
worse prognosis. Though the last decade has seen major advances in the novel features …

This volume of Advances in Genetics illustrates the series goal to publish the most current,
up-to-date reviews in the field of molecular and human genetics. This volume deviates from …

GATA1 is an essential transcriptional regulator of myeloid hematopoietic differentiation
towards red blood cells. During erythroid differentiation, GATA1 forms different complexes …

Chromosomal inversion and translocation between 3q21 and 3q26 [inv (3)(q21. 3q26. 2)
and t (3; 3)(q21. 3; q26. 2), respectively] give rise to acute myeloid leukemia (AML) and …