A review of NMR analysis in polysaccharide structure and conformation: Progress, challenge and perspective

JQ Wang, JY Yin, SP Nie, MY Xie - Food Research International, 2021 - Elsevier
Nuclear magnetic resonance (NMR) has been widely used as an analytical chemistry
technique to investigate the molecular structure and conformation of polysaccharides …

Primary structure of glycans by NMR spectroscopy

C Fontana, G Widmalm - Chemical Reviews, 2023 - ACS Publications
Glycans, carbohydrate molecules in the realm of biology, are present as biomedically
important glycoconjugates and a characteristic aspect is that their structures in many …

[HTML][HTML] Applications of infrared spectroscopy in polysaccharide structural analysis: Progress, challenge and perspective

T Hong, JY Yin, SP Nie, MY Xie - Food chemistry: X, 2021 - Elsevier
Polysaccharides are important biomacromolecules with numerous beneficial functions and a
wide range of industrial applications. Functions and properties of polysaccharides are …

Mass spectrometry-based techniques to elucidate the sugar code

M Grabarics, M Lettow, C Kirschbaum, K Greis… - Chemical …, 2021 - ACS Publications
Cells encode information in the sequence of biopolymers, such as nucleic acids, proteins,
and glycans. Although glycans are essential to all living organisms, surprisingly little is …

Direct observation of glycans bonded to proteins and lipids at the single-molecule level

K Anggara, L Sršan, T Jaroentomeechai, X Wu… - Science, 2023 - science.org
Proteins and lipids decorated with glycans are found throughout biological entities, playing
roles in biological functions and dysfunctions. Current analytical strategies for these glycan …

Glycoinformatics in the artificial intelligence era

D Bojar, F Lisacek - Chemical Reviews, 2022 - ACS Publications
Artificial intelligence (AI) methods have been and are now being increasingly integrated in
prediction software implemented in bioinformatics and its glycoscience branch known as …

Advances in glycoside and oligosaccharide synthesis

CJ Crawford, PH Seeberger - Chemical Society Reviews, 2023 - pubs.rsc.org
The structural complexity of glycans poses a serious challenge in the chemical synthesis of
glycosides, oligosaccharides and glycoconjugates. Glycan complexity, determined by …

Sialic acid O-acetylation patterns and glycosidic linkage type determination by ion mobility-mass spectrometry

GM Vos, KC Hooijschuur, Z Li, J Fjeldsted… - Nature …, 2023 - nature.com
O-acetylation is a common modification of sialic acids that has been implicated in a
multitude of biological and disease processes. A lack of analytical methods that can …

A Nanopore‐Based Saccharide Sensor

S Zhang, Z Cao, P Fan, Y Wang, W Jia… - Angewandte Chemie …, 2022 - Wiley Online Library
Saccharides play critical roles in many forms of cellular activities. Saccharide structures are
however complicated and similar, setting a technical hurdle for direct identification …

Mapping the acetylamino and carboxyl groups on glycans by engineered α-hemolysin nanopores

B Xia, J Fang, S Ma, M Ma, G Yao, T Li… - Journal of the …, 2023 - ACS Publications
Glycan is a crucial class of biological macromolecules with important biological functions.
Functional groups determine the chemical properties of glycans, which further affect their …