[HTML][HTML] The influence of sex hormones in liver function and disease

A Kasarinaite, M Sinton, PTK Saunders, DC Hay - Cells, 2023 - mdpi.com
The liver performs a multitude of bodily functions, whilst retaining the ability to regenerate
damaged tissue. In this review, we discuss sex steroid biology, regulation of mammalian …

[HTML][HTML] Endocrine disruptors and prostate cancer

M Corti, S Lorenzetti, A Ubaldi, R Zilli… - International Journal of …, 2022 - mdpi.com
The role of endocrine disruptors (EDs) in the human prostate gland is an overlooked issue
even though the prostate is essential for male fertility. From experimental models, it is known …

[HTML][HTML] Eighty years of targeting androgen receptor activity in prostate cancer: the fight goes on

E Estébanez-Perpiñá, CL Bevan, IJ McEwan - Cancers, 2021 - mdpi.com
Simple Summary Prostate cancer is the second most common cancer in men world-wide,
with nearly 1.3 million new cases each year, and over the next twenty years the incidence …

[HTML][HTML] No evidence for the immunocompetence handicap hypothesis in male humans

J Nowak, B Pawłowski, B Borkowska, D Augustyniak… - Scientific reports, 2018 - nature.com
The observations that testosterone might be immunosuppressive, form the basis for the
immunocompetence handicap hypothesis (ICHH). According to ICHH only high-quality …

[HTML][HTML] Androgen receptor signaling inhibitors: post-chemotherapy, pre-chemotherapy and now in castration-sensitive prostate cancer

N Mitsiades, S Kaochar - Endocrine-Related Cancer, 2021 - erc.bioscientifica.com
Based on pioneering work by Huggins, Hodges and others, hormonal therapies have been
established as an effective approach for advanced prostate cancer (PC) for the past eight …

[HTML][HTML] Meta-analysis of microRNAs expression in head and neck cancer: uncovering association with outcome and mechanisms

J Lubov, M Maschietto, I Ibrahim, A Mlynarek, M Hier… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Head and neck squamous cell carcinoma (HNSCC) is often diagnosed at advanced stages,
incurring significant high mortality and morbidity. This review explored the risk stratification …

Autopsy study of testicles in COVID-19: upregulation of immune-related genes and downregulation of testis-specific genes

A Basolo, AM Poma, E Macerola… - The Journal of …, 2023 - academic.oup.com
Abstract Context Infection by SARS-CoV-2 may be associated with testicular dysfunction that
could affect male fertility. Objective Testicles of fatal COVID-19 cases were investigated to …

[HTML][HTML] Estrogens and androgens in plants: the last 20 years of studies

A Janeczko - Plants, 2021 - mdpi.com
Although the only known steroid hormones in plants are brassinosteroids, interestingly,
mammalian steroid hormones such as androgens or estrogens are also part of the plant …

Androgens and Parkinson's disease: a review of human studies and animal models

M Bourque, D Soulet, T Di Paolo - Androgens: Clinical Research …, 2021 - liebertpub.com
Parkinson's disease (PD) is the second most common neurodegenerative disorder after
Alzheimer's disease. A greater prevalence and incidence of PD are reported in men than in …

[HTML][HTML] Hormone-related cancer and autoimmune diseases: a complex interplay to be discovered

A Losada-García, SA Cortés-Ramírez… - Frontiers in …, 2022 - frontiersin.org
Neoplasic transformation is a continuous process that occurs in the body. Even before
clinical signs, the immune system is capable of recognizing these aberrant cells and …