[HTML][HTML] Emerging Role of Circulating Cell-Free RNA as a Non-Invasive Biomarker for Hepatocellular Carcinoma
D Shetti, VR Mallela, W Ye, M Sharif… - Critical Reviews in …, 2024 - Elsevier
Hepatocellular carcinoma (HCC) is a severe neoplastic disease associated with high
morbidity and mortality rates. HCC is often detected at advanced stages leading to …
morbidity and mortality rates. HCC is often detected at advanced stages leading to …
Metabolic Enzyme SLC27A5 Regulates PIP4K2A pre‐mRNA Splicing as a Noncanonical Mechanism to Suppress Hepatocellular Carcinoma Metastasis
D Nie, X Tang, H Deng, X Yang, J Tao, F Xu… - Advanced …, 2024 - Wiley Online Library
Solute carrier family 27 member 5, a key enzyme in fatty acid transport and bile acid
metabolism in the liver, is frequently expressed in low quantities in patients with …
metabolism in the liver, is frequently expressed in low quantities in patients with …
Extensive Alternative Splicing Patterns in Systemic Lupus Erythematosus Highlight Sexual Differences
D Kosmara, S Papanikolaou, C Nikolaou, G Bertsias - Cells, 2023 - mdpi.com
Substantial evidence highlights divergences in immune responses between men and
women. Women are more susceptible to autoimmunity, whereas men suffer from the more …
women. Women are more susceptible to autoimmunity, whereas men suffer from the more …
[HTML][HTML] METTL3-Mediated LINC00475 Alternative Splicing Promotes Glioma Progression by Inducing Mitochondrial Fission
Y Yan, A Luo, S Liu, M Cai, X Liu, X Zhang, S Zhang… - Research, 2024 - spj.science.org
Mitochondrial fission promotes glioma progression. The function and regulation
mechanisms of lncRNAs in glioma mitochondrial fission are unclear. The expression of …
mechanisms of lncRNAs in glioma mitochondrial fission are unclear. The expression of …
The war between the immune system and the tumor-using immune biomarkers as tracers
K Yang, R Lu, J Mei, K Cao, T Zeng, Y Hua, X Huang… - Biomarker …, 2024 - Springer
Nowadays, immunotherapy is one of the most promising anti-tumor therapeutic strategy.
Specifically, immune-related targets can be used to predict the efficacy and side effects of …
Specifically, immune-related targets can be used to predict the efficacy and side effects of …
Exploring precision treatments in immune‐mediated inflammatory diseases: Harnessing the infinite potential of nucleic acid delivery
L Xu, Z Shao, X Fang, Z Xin, S Zhao, H Zhang… - …, 2024 - Wiley Online Library
Immune‐mediated inflammatory diseases (IMIDs) impose an immeasurable burden on
individuals and society. While the conventional use of immunosuppressants and disease …
individuals and society. While the conventional use of immunosuppressants and disease …
Circulating tumor cell clustering modulates RNA splicing and polyadenylation to facilitate metastasis
Q Wu, Z Gu, B Shang, D Wan, Q Zhang, X Zhang, P Xie… - Cancer Letters, 2024 - Elsevier
Circulating tumor cell (CTC) clusters exhibit significantly higher metastatic potential
compared to single CTCs. However, the underlying mechanism behind this phenomenon …
compared to single CTCs. However, the underlying mechanism behind this phenomenon …
Shaping Oncogenic Microenvironments: Contribution of Fibronectin
G Guerrero-Barberà, N Burday… - Frontiers in Cell and …, 2024 - frontiersin.org
The extracellular matrix (ECM) is a complex network of proteins and glycans, dynamically
remodeled and specifically tailored to the structure/function of each organ. The malignant …
remodeled and specifically tailored to the structure/function of each organ. The malignant …
Small molecules modulating RNA splicing: a review of targets and future perspectives
In eukaryotic cells, RNA splicing is crucial for gene expression. Dysregulation of this process
can result in incorrect mRNA processing, leading to aberrant gene expression patterns …
can result in incorrect mRNA processing, leading to aberrant gene expression patterns …
Metabolic heterogeneity in clear cell renal cell carcinoma revealed by single-cell RNA sequencing and spatial transcriptomics
G Yang, J Cheng, J Xu, C Shen, X Lu, C He… - Journal of Translational …, 2024 - Springer
Background Clear cell renal cell carcinoma is a prototypical tumor characterized by
metabolic reprogramming, which extends beyond tumor cells to encompass diverse cell …
metabolic reprogramming, which extends beyond tumor cells to encompass diverse cell …