[HTML][HTML] Current research trends of nanomedicines

Q Liu, J Zou, Z Chen, W He, W Wu - Acta Pharmaceutica Sinica B, 2023 - Elsevier
Owing to the inherent shortcomings of traditional therapeutic drugs in terms of inadequate
therapeutic efficacy and toxicity in clinical treatment, nanomedicine designs have received …

[HTML][HTML] Phosphatidylcholine (PCL) fortified nano-phytopharmaceuticals for improvement of therapeutic efficacy

DU Kapoor, M Gaur, A Parihar, BG Prajapati… - EXCLI …, 2023 - ncbi.nlm.nih.gov
Phytopharmaceuticals, derived from plants, are increasingly recognized for their potential
therapeutic benefits. However, their effectiveness is often hindered by challenges such as …

Dexamethasone liposomes alleviate osteoarthritis in miR-204/-211-deficient mice by repolarizing synovial macrophages to M2 phenotypes

H Teng, S Chen, K Fan, Q Wang, B Xu… - Molecular …, 2023 - ACS Publications
We undertook this study to investigate the effects and mechanisms of dexamethasone
liposome (Dex-Lips) on alleviating destabilization of the medial meniscus (DMM)-induced …

In vitro-in vivo correlation in nanocarriers: From protein corona to therapeutic implications

TG Agnihotri, A Alexander, M Agrawal… - Journal of Controlled …, 2023 - Elsevier
Understanding and establishing a link between the physicochemical characteristics of
nanoparticles (NPs) and their biological interactions poses to be a great challenge in the …

Nano-Based Drug Delivery Systems: Potential Developments in the Therapy of Metastatic Osteosarcoma—A Narrative Review

Y Luo, M Sun, L Tan, T Li, L Min - Pharmaceutics, 2023 - mdpi.com
Osteosarcoma, a predominant malignant bone tumor, poses significant challenges due to its
high metastatic and recurrent nature. Although various therapeutic strategies are currently in …

Oral efficacy of a diselenide compound loaded in nanostructured lipid carriers in a murine model of visceral leishmaniasis

M Etxebeste-Mitxeltorena, E Moreno… - ACS Infectious …, 2021 - ACS Publications
Leishmaniasis urgently needs new oral treatments, as it is one of the most important
neglected tropical diseases that affects people with poor resources. The drug discovery …

[HTML][HTML] Fast and reliable analysis of pH-responsive nanocarriers for drug delivery using microfluidic tools

B García-Merino, E Bringas, I Ortiz - International Journal of Pharmaceutics, 2023 - Elsevier
During the last decades, there has been growing interest in the application of functionalized
mesoporous nanomaterials as stimuli-responsive carriers for drug delivery. However, at …

Revisiting the in-vitro and in-vivo considerations for in-silico modelling of complex injectable drug products

A Dabke, S Ghosh, P Dabke, K Sawant… - Journal of Controlled …, 2023 - Elsevier
Complex injectable drug products (CIDPs) have often been developed to modulate the
pharmacokinetics along with efficacy for therapeutic agents used for remediation of chronic …

Quercetin nanocrystals prepared by a novel technique improve the dissolution rate and antifibrotic activity of quercetin

P Cheshmehnoor, S Rabbani, A Haeri - Nanomedicine, 2023 - Taylor & Francis
Aim: To develop quercetin nanocrystals by a simple approach and to evaluate their in vivo
antifibrotic efficacy. Materials & methods: Nanosuspensions were fabricated by a thin-film …

Advanced 3D and 4D microstructure study of single granule formation for pharmaceutical powders using synchrotron x‐ray imaging

S Zeinali Danalou, C Blocka, J Yang, N Zhu… - AIChE …, 2023 - Wiley Online Library
Monitoring the microstructure of the granule in the wet granulation process could play a
decisive role in obtaining high‐quality granules. Due to the complex, fast and opaque nature …