[HTML][HTML] Current research trends of nanomedicines
Owing to the inherent shortcomings of traditional therapeutic drugs in terms of inadequate
therapeutic efficacy and toxicity in clinical treatment, nanomedicine designs have received …
therapeutic efficacy and toxicity in clinical treatment, nanomedicine designs have received …
[HTML][HTML] Phosphatidylcholine (PCL) fortified nano-phytopharmaceuticals for improvement of therapeutic efficacy
DU Kapoor, M Gaur, A Parihar, BG Prajapati… - EXCLI …, 2023 - ncbi.nlm.nih.gov
Phytopharmaceuticals, derived from plants, are increasingly recognized for their potential
therapeutic benefits. However, their effectiveness is often hindered by challenges such as …
therapeutic benefits. However, their effectiveness is often hindered by challenges such as …
Dexamethasone liposomes alleviate osteoarthritis in miR-204/-211-deficient mice by repolarizing synovial macrophages to M2 phenotypes
H Teng, S Chen, K Fan, Q Wang, B Xu… - Molecular …, 2023 - ACS Publications
We undertook this study to investigate the effects and mechanisms of dexamethasone
liposome (Dex-Lips) on alleviating destabilization of the medial meniscus (DMM)-induced …
liposome (Dex-Lips) on alleviating destabilization of the medial meniscus (DMM)-induced …
In vitro-in vivo correlation in nanocarriers: From protein corona to therapeutic implications
Understanding and establishing a link between the physicochemical characteristics of
nanoparticles (NPs) and their biological interactions poses to be a great challenge in the …
nanoparticles (NPs) and their biological interactions poses to be a great challenge in the …
Nano-Based Drug Delivery Systems: Potential Developments in the Therapy of Metastatic Osteosarcoma—A Narrative Review
Y Luo, M Sun, L Tan, T Li, L Min - Pharmaceutics, 2023 - mdpi.com
Osteosarcoma, a predominant malignant bone tumor, poses significant challenges due to its
high metastatic and recurrent nature. Although various therapeutic strategies are currently in …
high metastatic and recurrent nature. Although various therapeutic strategies are currently in …
Oral efficacy of a diselenide compound loaded in nanostructured lipid carriers in a murine model of visceral leishmaniasis
M Etxebeste-Mitxeltorena, E Moreno… - ACS Infectious …, 2021 - ACS Publications
Leishmaniasis urgently needs new oral treatments, as it is one of the most important
neglected tropical diseases that affects people with poor resources. The drug discovery …
neglected tropical diseases that affects people with poor resources. The drug discovery …
[HTML][HTML] Fast and reliable analysis of pH-responsive nanocarriers for drug delivery using microfluidic tools
B García-Merino, E Bringas, I Ortiz - International Journal of Pharmaceutics, 2023 - Elsevier
During the last decades, there has been growing interest in the application of functionalized
mesoporous nanomaterials as stimuli-responsive carriers for drug delivery. However, at …
mesoporous nanomaterials as stimuli-responsive carriers for drug delivery. However, at …
Revisiting the in-vitro and in-vivo considerations for in-silico modelling of complex injectable drug products
Complex injectable drug products (CIDPs) have often been developed to modulate the
pharmacokinetics along with efficacy for therapeutic agents used for remediation of chronic …
pharmacokinetics along with efficacy for therapeutic agents used for remediation of chronic …
Quercetin nanocrystals prepared by a novel technique improve the dissolution rate and antifibrotic activity of quercetin
Aim: To develop quercetin nanocrystals by a simple approach and to evaluate their in vivo
antifibrotic efficacy. Materials & methods: Nanosuspensions were fabricated by a thin-film …
antifibrotic efficacy. Materials & methods: Nanosuspensions were fabricated by a thin-film …
Advanced 3D and 4D microstructure study of single granule formation for pharmaceutical powders using synchrotron x‐ray imaging
S Zeinali Danalou, C Blocka, J Yang, N Zhu… - AIChE …, 2023 - Wiley Online Library
Monitoring the microstructure of the granule in the wet granulation process could play a
decisive role in obtaining high‐quality granules. Due to the complex, fast and opaque nature …
decisive role in obtaining high‐quality granules. Due to the complex, fast and opaque nature …