Resveratrol, a constituent of red wine, has long been suspected to have cardioprotective
effects. Interest in this compound has been renewed in recent years, first from its …

Introduction 3. Mechanisms of Action 3.1. Regulation of Bcl-2 family members 3.2.
Regulation of cell cycle 3.3. Regulation of MAP kinase 3.4. Generation of Reactive Oxygen …

Oxidative stress has been implicated in pathophysiology of diabetic neuropathy. All the
pathways responsible for development of diabetic neuropathy are linked to oxidative stress …

Background: Despite advances in our understanding of basic mechanisms driving post-
surgical pain, treating incision-induced pain remains a major clinical challenge. Moreover …

Phenolic phytochemicals include flavonoids, phenolic acids, tannins, lignans, coumarins,
quinones, xanthones, cucurmin, and several other plant compounds owing hydroxyl group …

Ovarian Granulosa Cells (GCs) are known to proliferate in the developing follicle and
undergo several biochemical processes during folliculogenesis. They represent a …

The mechanism by which COX inhibitors exert their analgesic effect is well established.
However, data show no direct correlation between drug concentrations in plasma and the …

Background There is current interest in understanding the molecular mechanisms of tumor-
induced bone pain. Accumulated evidence shows that endogenous formaldehyde …

This study characterises some of the mechanisms and mediators involved in the orofacial
nociception triggered by injection of formalin into the upper lip of the rat, by assessing the …

The effects of an ethanol extract of the aerial parts of Ruta chalepensis on the central
nervous system (CNS) and LD50 determination were studied in mice. A crude extract was …