Pharmacokinetic aspects of nanoparticle-in-matrix drug delivery systems for oral/buccal delivery
RC Feitosa, DC Geraldes… - Frontiers in …, 2019 - frontiersin.org
Oral route maintains its predominance among the ones used for drug delivery, especially
when medicines are self-administered. If the dosage form is solid, therapy gains in dose …
when medicines are self-administered. If the dosage form is solid, therapy gains in dose …
Self-emulsifying systems for delivery of bioactive compounds from natural origin
MC de Oliveira, ML Bruschi - AAPS PharmSciTech, 2022 - Springer
Nature has been used as therapeutic resources in the treatment of diseases for many years.
However, some natural compounds have poor water solubility. Therefore, physicochemical …
However, some natural compounds have poor water solubility. Therefore, physicochemical …
[HTML][HTML] Thermal degradation and kinetics stability studies of oil palm (Elaeis Guineensis) biomass-derived lignin nanoparticle and its application as an emulsifying …
In this paper, lignin was extracted from oil palm empty fruit branch fibers by using a soda
pulping process. The homogenizing method was used to reduce the size of lignin into …
pulping process. The homogenizing method was used to reduce the size of lignin into …
Formulation development of mirtazapine liquisolid compacts: optimization using central composite design
Mirtazapine is a tetracyclic anti-depressant with poor water solubility. The aim of this study
was to improve the dissolution rate of mirtazapine by delivering the drug as a liquisolid …
was to improve the dissolution rate of mirtazapine by delivering the drug as a liquisolid …
The importance of the coating material type and amount in the preparation of liquisolid systems based on magnesium aluminometasilicate carrier
B Vraníková, P Svačinová, J Marushka… - European Journal of …, 2021 - Elsevier
Albeit the preparation of liquisolid systems represents an innovative approach to enhance
the dissolution of poorly soluble drugs, their broader utilization is still limited mainly due to …
the dissolution of poorly soluble drugs, their broader utilization is still limited mainly due to …
[HTML][HTML] The most recent advances in liquisolid technology: Perspectives in the pharmaceutical industry
Hydrophobic drugs exhibit altered bioavailability and pose other challenges at an industrial
level due to their poor solubility and dissolution rates. In addition, poor flowability …
level due to their poor solubility and dissolution rates. In addition, poor flowability …
The Potential of macroporous silica—Nanocrystalline cellulose combination for formulating dry emulsion systems with improved flow properties: A DoE study
M Pohlen, L Pirker, R Dreu - Pharmaceutics, 2021 - mdpi.com
The objective of this study was to explore the possible use of a new combination of two
excipients, ie, nanocrystalline cellulose (NCC) and macroporous silica (MS), as matrix …
excipients, ie, nanocrystalline cellulose (NCC) and macroporous silica (MS), as matrix …
Gastroretentive Sustained-Release Tablets Combined with a Solid Self-Micro-Emulsifying Drug Delivery System Adsorbed onto Fujicalin®
Y Omachi - AAPS PharmSciTech, 2022 - Springer
Gastroretentive drug delivery systems (GRDDS) get retained in the stomach for a long time,
thus facilitating the absorption of drugs in the upper gastrointestinal tract. However, drugs …
thus facilitating the absorption of drugs in the upper gastrointestinal tract. However, drugs …
Combining liquisolid and co-grinding techniques to enhance the dissolution rate of celecoxib
Purpose The classic liquisolid technique is used to enhance the dissolution rate of poorly
water-soluble drugs, but in some cases, it is impossible to reach the desired dissolution rate …
water-soluble drugs, but in some cases, it is impossible to reach the desired dissolution rate …
Hybrid nanomaterials as next-generation corrosion inhibitors for metals and alloys
Corrosion is a major problem in many industries, causing economic losses and safety and
environmental issues. Traditional methods fall short of modern demands, so innovative …
environmental issues. Traditional methods fall short of modern demands, so innovative …