Mercury (Hg) has adverse effects on humans and wildlife. Hg exposure can cause
significant alterations in DNA methylation, an epigenetic modification that causes various …

Background Prostate cancer has a variable clinical behaviour with frequently unpredictable
outcome. DNA methylation plays an important role in determining the biology of cancer but …

Prostate development, benign hyperplasia and cancer involve androgen and growth factor
signaling as well as stromal–epithelial interactions. We review how DNA methylation …

Background DNA methylation alterations have emerged as hallmarks of cancer and have
been proposed as screening, prognostic, and predictive biomarkers. Traditional approaches …

Limitations of current diagnostic and prognostic tools for prostate cancer (PC) have led to
over-diagnosis and over-treatment. Here, we investigate the biomarker potential of the …

ACBD3 overexpression has previously been found to correlate with worse prognosis for
breast cancer patients and, as an incredibly diverse protein in both function and cellular …

Background Dyslipidemia, which is characterized by an unfavorable lipid profile, is a key risk
factor for cardiovascular disease (CVD). Understanding the relationships between …

Abstract Cyanocobalamin (Vitamin B12, VB12) and Folic acid (Vitamin B9, VB9) deficiency
leads to anemia in women. We have recently shown low VB12 and VB9 levels in the serum …

Chromatin accessibility is associated with gene regulatory elements and gene transcription.
It has been found to be tissue specific and in more recent studies, cancer specific …

Purpose Definitive chemoradiotherapy (dCRT) is one of the standard treatments for
esophageal squamous cell carcinoma. Patients with a response to dCRT have a better …