[HTML][HTML] Anakinra Pilot–a clinical trial to demonstrate safety, feasibility and pharmacokinetics of interleukin 1 receptor antagonist in preterm infants
EA Green, D Metz, R Galinsky, R Atkinson… - Frontiers in …, 2022 - frontiersin.org
Background Bronchopulmonary dysplasia (BPD), its complication pulmonary hypertension
(BPD-PH) and preterm brain and gut injury lead to significant morbidity and mortality in …
(BPD-PH) and preterm brain and gut injury lead to significant morbidity and mortality in …
Establishment of a children's Drugs and Therapeutics Committee to ensure evidence‐based and cost‐effective medical treatment for children
SS Holst, CH Møller, C Vermehren… - British Journal of …, 2024 - Wiley Online Library
The prevalence of undocumented medical treatments among children is a significant issue,
as well as many EU countries lack access to newly developed children‐friendly medicines …
as well as many EU countries lack access to newly developed children‐friendly medicines …
[HTML][HTML] Commonly used medications for respiratory and cardiovascular support in neonates: Evidence, knowledge gaps, and future perspectives
E Agakidou, A Kontou, E Chatziioannidis, W Chotas… - Global Pediatrics, 2024 - Elsevier
Critically ill neonates admitted to neonatal intensive care units require specialized
pharmacological treatment due to various medical conditions. However, despite the …
pharmacological treatment due to various medical conditions. However, despite the …
Massive presence of off‐label medicines in Danish neonatal departments: A nationwide survey using national hospital purchase data
C Gade, S Trolle, ML Mørk, A Lewis… - Pharmacology …, 2023 - Wiley Online Library
There is currently insufficient knowledge of gestational age dependent medicine disposition
in neonates. Accordingly, the use of off‐label medication, ie, use of medicines outside its …
in neonates. Accordingly, the use of off‐label medication, ie, use of medicines outside its …
Novel approaches to postnatal prophylaxis to eliminate vertical transmission of HIV
T Ruel, M Penazzato, JM Zech, M Archary… - … Health: Science and …, 2023 - ghspjournal.org
Novel Approaches to Postnatal Prophylaxis to Eliminate Vertical Transmission of HIV | Global
Health: Science and Practice Skip to main content Main menu Content Current Issue Advance …
Health: Science and Practice Skip to main content Main menu Content Current Issue Advance …
[HTML][HTML] Ontogeny of CYP3A and UGT activity in preterm piglets: a translational model for drug metabolism in preterm newborns
L Buyssens, A Valenzuela, S Prims, M Ayuso… - Frontiers in …, 2023 - frontiersin.org
Despite considerable progress in understanding drug metabolism in the human pediatric
population, data remains scarce in preterm neonates. Improving our knowledge of the …
population, data remains scarce in preterm neonates. Improving our knowledge of the …
Subgroup identification-based model selection to improve the predictive performance of individualized dosing
Currently, model-informed precision dosing uses one population pharmacokinetic model
that best fits the target population. We aimed to develop a subgroup identification-based …
that best fits the target population. We aimed to develop a subgroup identification-based …
[HTML][HTML] Pharmacokinetics of drugs: newborn perspective
N Bansal, S Momin, R Bansal, SKRG Venkata… - Pediatric …, 2024 - pm.amegroups.org
Safe and effective drug administration are pivotal goals of neonatal pharmacokinetics.
Integrated knowledge of evolving pharmacokinetic principles, physiological characteristics …
Integrated knowledge of evolving pharmacokinetic principles, physiological characteristics …
[HTML][HTML] Approaches to Reduce the Side Effects of Antibiotic Therapy in Premature Newborns
Significant risk of side effects of drug therapy in newborns, especially in premature
neonates, is associated with immaturity of a number of enzyme systems and …
neonates, is associated with immaturity of a number of enzyme systems and …
Novel Approaches to Postnatal Prophylaxis to Eliminate Vertical Transmission of HIV.
M Penazzato, J Zech, M Archary… - … Health: Science and …, 2023 - escholarship.org
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COMMENTARY Novel Approaches to Postnatal Prophylaxis to Eliminate Vertical Transmission …
COMMENTARY Novel Approaches to Postnatal Prophylaxis to Eliminate Vertical Transmission …