Cinchona is a plant used in traditional malaria treatment. This review aims to examine
pharmacological activities to increase the benefits and uses of the bioactive compounds …

Patients with sleep‐related motor and behavioral disorders present to a variety of
subspecialty clinics (neurology, sleep medicine, respiratory medicine, psychiatry) …

Background and objective Restless legs syndrome/Willis-Ekbom Disease (RLS/WED) is one
of the most prevalent sleep disorders. There are contradicting data about the effectiveness of …

Background Nocturnal leg cramps (NLC) are common and poorly understood. Objective To
determine the prevalence of NLC and associations with cardiometabolic, sleep, and …

Background Approximately one out of two individuals over the age of 60 suffers from
nocturnal leg cramps. These often have an important impact on the person's quality of life …

Abstract Objective Studies that examined Internet searches for restless legs and leg cramps
have found a strong seasonal effect with peaks in summer and troughs in winter months …

Objectives We investigated if neuromuscular electrical stimulation (NMES) of calf muscles
prevents spontaneous calf cramps. Materials and Methods In 19 individuals affected by …

PURPOSE Nocturnal leg cramps are a specific kind of cramps affecting almost one-half of
patients aged 60 years and older. They reduce patients' quality of sleep and have a negative …

Abstract Nocturnal Legs Cramps are a frequent disorder, which have a negative impact on
quality of life, particularly among patients over 60 years old. Lifestyle factors such as alcohol …

Sleep-related movement disorders (SRMD) are common, often troublesome, conditions in
the elderly. Although these disorders can impact people of all ages, there are different …