Chronic oligodendrocyte injury in central nervous system pathologies
Myelin, the membrane surrounding neuronal axons, is critical for central nervous system
(CNS) function. Injury to myelin-forming oligodendrocytes (OL) in chronic neurological …
(CNS) function. Injury to myelin-forming oligodendrocytes (OL) in chronic neurological …
Injectable hydrogels in stroke and spinal cord injury treatment: a review on hydrogel materials, cell–matrix interactions and glial involvement
PH Lin, Q Dong, SY Chew - Materials Advances, 2021 - pubs.rsc.org
Central nervous system (CNS) pathologies, such as stroke and spinal cord injury, remain
debilitating issues due to the inhibitory environment in the CNS. Many research works have …
debilitating issues due to the inhibitory environment in the CNS. Many research works have …
Gait performance of adolescent mice assessed by the CatWalk XT depends on age, strain and sex and correlates with speed and body weight
C Pitzer, B Kurpiers, A Eltokhi - Scientific reports, 2021 - nature.com
The automatization of behavioral tests assessing motor activity in rodent models is important
for providing robust and reproducible results and evaluating new therapeutics. The CatWalk …
for providing robust and reproducible results and evaluating new therapeutics. The CatWalk …
Long-term effects of neural precursor cell transplantation on secondary injury processes and functional recovery after severe cervical contusion-compression spinal …
A Younsi, G Zheng, L Riemann, M Scherer… - International journal of …, 2021 - mdpi.com
Cervical spinal cord injury (SCI) remains a devastating event without adequate treatment
options despite decades of research. In this context, the usefulness of common preclinical …
options despite decades of research. In this context, the usefulness of common preclinical …
Gait analysis using animal models of peripheral nerve and spinal cord injuries
G Isvoranu, E Manole, M Neagu - Biomedicines, 2021 - mdpi.com
The present review discusses recent data regarding rodent models of spinal cord and
peripheral nerve injuries in terms of gait analysis using the CatWalk system (CW), an …
peripheral nerve injuries in terms of gait analysis using the CatWalk system (CW), an …
Icariin promotes survival, proliferation, and differentiation of neural stem cells in vitro and in a rat model of Alzheimer's disease
D Ma, L Zhao, L Zhang, Y Li, L Zhang… - Stem cells …, 2021 - Wiley Online Library
Alzheimer's disease (AD) involves the degeneration of cholinergic neurons in the basal
forebrain. Neural stem cell (NSC) transplantation has emerged as a promising therapeutic …
forebrain. Neural stem cell (NSC) transplantation has emerged as a promising therapeutic …
Muscle-derived stem cell exosomes with overexpressed miR-214 promote the regeneration and repair of rat sciatic nerve after crush injury to activate the JAK2/STAT3 …
X Zeng, W Bian, Z Liu, J Li, S Ren, J Zhang… - Frontiers in Molecular …, 2023 - frontiersin.org
Introduction This study aimed to investigate the effect of muscle-derived stem cell (MDSC)
exosomes with overexpressed miR-214 on the regeneration and repair of rat sciatic nerve …
exosomes with overexpressed miR-214 on the regeneration and repair of rat sciatic nerve …
Reducing host aldose reductase activity promotes neuronal differentiation of transplanted neural stem cells at spinal cord injury sites and facilitates locomotion …
K Zhang, WC Lu, M Zhang, Q Zhang… - Neural Regeneration …, 2022 - journals.lww.com
Neural stem cell (NSC) transplantation is a promising strategy for replacing lost neurons
following spinal cord injury. However, the survival and differentiation of transplanted NSCs is …
following spinal cord injury. However, the survival and differentiation of transplanted NSCs is …
The sonic hedgehog pathway modulates survival, proliferation, and differentiation of neural progenitor cells under inflammatory stress in vitro
M Tail, H Zhang, G Zheng, M Hatami, T Skutella… - Cells, 2022 - mdpi.com
The Sonic Hedgehog protein (Shh) has been extensively researched since its discovery in
1980. Its crucial role in early neurogenesis and endogenous stem cells of mature brains, as …
1980. Its crucial role in early neurogenesis and endogenous stem cells of mature brains, as …
Coordination function index: A novel indicator for assessing hindlimb locomotor recovery in spinal cord injury rats based on catwalk gait parameters
S Liu, Q Wu, L Wang, C Xing, J Guo, B Li, H Ma… - Behavioural Brain …, 2024 - Elsevier
In preclinical studies of spinal cord injury (SCI), behavioral assessments are crucial for
evaluating treatment effectiveness. Commonly used methods include Basso, Beattie …
evaluating treatment effectiveness. Commonly used methods include Basso, Beattie …