Background: Hydrogen sulfide (H2S) has antihypertension and anti-inflammatory effects,
and its endogenous-generation key enzyme cystathionine γ lyase (CSE) is expressed in …

Dementia is growing at an alarming rate worldwide. Although Alzheimer disease is the
leading cause, over 50% of individuals diagnosed with Alzheimer disease have vascular …

The link between inappropriate salt retention in the kidney and hypertension is well
recognized. However, growing evidence suggests that the immune system can play …

Giant cell arteritis (GCA) is a granulomatous vasculitis of the aorta and its medium-sized
branch vessels. CD4 T cells, macrophages, and dendritic cells (DCs) build granulomatous …

Cardiovascular diseases (CVDs) are the main contributors to global morbidity and mortality.
Major pathogenic phenotypes of CVDs include the development of endothelial dysfunction …

Perioperative hypotension has been repeatedly associated with organ injury and worse
outcome, yet many interventions to reduce morbidity by attempting to avoid or reverse …

Background: Renal T cells contribute importantly to hypertension, but the underlying
mechanism is incompletely understood. We reported that CD8Ts directly stimulate distal …

Over the past decade, the immune system has emerged as an important component in the
aetiology of hypertension. There has been a blooming interest in the contribution of the gut …

Evidence from nonhuman animal models demonstrates an important role for immune cells in
hypertension, but immune cell changes in human hypertension are less clear. Using mass …

Increasing evidence indicates that hypertension and hypertensive end-organ damage are
not only mediated by hemodynamic injury. Inflammation also plays an important role in the …