Since their formal discovery in 1975, natural killer (NK) cells have always been proposed in
the literature as a potential treatment for cancer and viral infections. This recommendation …

Malignant expansion and rapid metastasis are the main limiting factors to successful
treatment of lung cancer. Messenger RNA (mRNA) tumor vaccines are a promising …

Aging results from the accumulation of molecular damage that impairs normal biochemical
processes. We previously reported that age‐linked damage to amino acid sequence NGR …

Antibodies targeting “immune checkpoints” have revolutionized cancer therapy by
reactivating tumor-resident cytotoxic lymphocytes, primarily CD8+ T cells. Interest in …

Introduction Soft tissue sarcomas (STS) are rare, heterogenous malignancies with an unmet
need for novel immunotherapies. Tumor infiltrating lymphocytes (TILs) have been linked with …

Simple Summary The disialoganglioside GD2 is produced at high levels by neuroblastomas
and other tumors of neuroectodermal origin, where its expression correlates with increased …

Radiotherapy (RT) is an important and effective cancer treatment method clinically. In the
tumor microenvironment (TME), RT can induce tumor-specific immune responses by …

Cancer represents the leading global driver of death and is recognized as a critical obstacle
to increasing life expectancy. In recent years, with the development of precision medicine …

In recent years, the development of bispecific antibodies (bsAbs) has been rapid, with many
new structures and target combinations being created. The boom in bsAbs has led to the …

NKG2D is an activating receptor of natural killer cells that recognizes stress-induced ligands
(NKG2DL) expressed by many tumor cells. Nevertheless, NKG2DL downregulation or …