CCL21, a secondary lymphoid tissue chemokine, plays an important role in generating an
effective anti-tumor immune response. In this study, a genetically modified CCL21 was …

Natural killer (NK)‐cell immunotherapy as an alternative to T‐cell immunotherapy has been
widely used in clinical cell immunotherapy of various tumors. Despite the surprising findings …

Background Different from other malignant gynecologic tumors, gestational trophoblastic
neoplasms (GTNs) exhibit an exceptionally high cure rate primarily through …

Human decidual natural killer (dNK) cells are a unique type of tissue-resident NK cells at the
maternal-fetal interface. dNK cells are likely to have pivotal roles during pregnancy …

The short-lived nature and heterogeneity of Natural Killer (NK) cells limit the development of
NK cell-based therapies, despite their proven safety and efficacy against cancer. Here, we …

Natural killer (NK) cells are crucial in the innate immune response and show promise in
cancer immunotherapy, but face challenges in activation and targeted gene delivery. In this …

Serine/threonine‐protein kinase B‐raf (BRAF) mutations are found in 8–15% of colorectal
cancer patients and identify a subset of tumors with poor outcome in the metastatic setting …

Gynecological cancers, including endometrial adenocarcinoma, significantly contribute to
cancer incidence and mortality worldwide. The immune system plays a significant role in …

DNA damage is a prevalent phenomenon in the context of cancer progression. Evidence
suggests that DNA damage responses (DDR) are pivotal in overcoming tumor immune …

Cytotoxic T lymphocytes recognize and kill cancer cells when the latter present antigenic
epitopes complexed with MHC class I molecules on their surface. In a recent Science paper …