[HTML][HTML] Mycotoxins affecting animals, foods, humans, and plants: Types, occurrence, toxicities, action mechanisms, prevention, and detoxification strategies—A revisit

CG Awuchi, EN Ondari, CU Ogbonna, AK Upadhyay… - Foods, 2021 - mdpi.com
Mycotoxins are produced by fungi and are known to be toxic to humans and animals.
Common mycotoxins include aflatoxins, ochratoxins, zearalenone, patulin, sterigmatocystin …

Fungal secondary metabolism: regulation, function and drug discovery

NP Keller - Nature Reviews Microbiology, 2019 - nature.com
One of the exciting movements in microbial sciences has been a refocusing and
revitalization of efforts to mine the fungal secondary metabolome. The magnitude of …

[HTML][HTML] Aflatoxins: Producing-molds, structure, health issues and incidence in Southeast Asian and Sub-Saharan African countries

N Benkerroum - International journal of environmental research and …, 2020 - mdpi.com
This review aims to update the main aspects of aflatoxin production, occurrence and
incidence in selected countries, and associated aflatoxicosis outbreaks. Means to reduce …

[HTML][HTML] Aflatoxins: A global concern for food safety, human health and their management

P Kumar, DK Mahato, M Kamle, TK Mohanta… - Frontiers in …, 2017 - frontiersin.org
The aflatoxin producing fungi, Aspergillus spp., are widely spread in nature and have
severely contaminated food supplies of humans and animals, resulting in health hazards …

[HTML][HTML] Aflatoxin biosynthesis and genetic regulation: A review

I Caceres, A Al Khoury, R El Khoury, S Lorber… - Toxins, 2020 - mdpi.com
The study of fungal species evolved radically with the development of molecular techniques
and produced new evidence to understand specific fungal mechanisms such as the …

[HTML][HTML] Aspergillus derived mycotoxins in food and the environment: Prevalence, detection, and toxicity

V Navale, KR Vamkudoth, S Ajmera, V Dhuri - Toxicology reports, 2021 - Elsevier
Aspergillus species are the paramount ubiquitous fungi that contaminate various food
substrates and produce biochemicals known as mycotoxins. Aflatoxins (AFTs), ochratoxin A …

[HTML][HTML] Aflatoxins: History, significant milestones, recent data on their toxicity and ways to mitigation

D Pickova, V Ostry, J Toman, F Malir - Toxins, 2021 - mdpi.com
In the early 1960s the discovery of aflatoxins began when a total of 100,000 turkey poults
died by hitherto unknown turkey “X” disease in England. The disease was associated with …

Oxidative cyclization in natural product biosynthesis

MC Tang, Y Zou, K Watanabe, CT Walsh… - Chemical …, 2017 - ACS Publications
Oxidative cyclizations are important transformations that occur widely during natural product
biosynthesis. The transformations from acyclic precursors to cyclized products can afford …

[HTML][HTML] Orange, red, yellow: biosynthesis of azaphilone pigments in Monascus fungi

W Chen, R Chen, Q Liu, Y He, K He, X Ding… - Chemical …, 2017 - pubs.rsc.org
Monascus azaphilone pigments (MonAzPs) are very widely used as food colorants, but their
biosynthetic pathway has remained poorly characterized for more than half a century. In this …

Fungal secondary metabolism—from biochemistry to genomics

NP Keller, G Turner, JW Bennett - Nature reviews microbiology, 2005 - nature.com
Much of natural product chemistry concerns a group of compounds known as secondary
metabolites. These low-molecular-weight metabolites often have potent physiological …