[HTML][HTML] The role of Epstein–Barr virus in nasopharyngeal carcinoma

ZY Su, PY Siak, CO Leong, SC Cheah - Frontiers in Microbiology, 2023 - frontiersin.org
Nasopharyngeal carcinoma (NPC) is a metastasis-prone malignancy closely associated
with the Epstein–Barr virus (EBV). Despite ubiquitous infection of EBV worldwide, NPC …

International consensus statement on allergy and rhinology: sinonasal tumors

EC Kuan, EW Wang, ND Adappa… - International forum of …, 2024 - Wiley Online Library
Background Sinonasal neoplasms, whether benign and malignant, pose a significant
challenge to clinicians and represent a model area for multidisciplinary collaboration in …

[HTML][HTML] m6A demethylase FTO renders radioresistance of nasopharyngeal carcinoma via promoting OTUB1-mediated anti-ferroptosis

WM Huang, ZX Li, YH Wu, ZL Shi, JL Mi, K Hu… - Translational …, 2023 - Elsevier
Radiotherapy is a valid treatment for nasopharyngeal carcinoma (NPC), and radioresistance
is the main cause of local NPC treatment failure. However, the underlying mechanisms and …

Plasma Epstein–Barr virus DNA and risk of future nasopharyngeal cancer

KCA Chan, WKJ Lam, A King, VS Lin, PPH Lee… - NEJM …, 2023 - evidence.nejm.org
Background We previously conducted a prospective study to show that nasopharyngeal
cancer (NPC) screening with circulating Epstein–Barr virus (EBV) DNA analysis can improve …

Current status and advances of immunotherapy in nasopharyngeal carcinoma

JY Xu, XL Wei, YQ Wang… - Therapeutic Advances in …, 2022 - journals.sagepub.com
The general immune landscape of nasopharyngeal carcinoma (NPC) renders
immunotherapy suitable for patients with NPC. Immune checkpoint inhibitors (ICIs) based on …

Functions of double‐negative B cells in autoimmune diseases, infections, and cancers

MKY Chung, L Gong, DLW Kwong, VHF Lee… - EMBO Molecular …, 2023 - embopress.org
Most mature B cells can be divided into four subtypes based on the expression of the
surface markers IgD and CD27: IgD+ CD27− naïve B cells, IgD+ CD27+ unswitched memory …

[HTML][HTML] Pembrolizumab monotherapy versus chemotherapy in platinum-pretreated, recurrent or metastatic nasopharyngeal cancer (KEYNOTE-122): an open-label …

ATC Chan, VHF Lee, RL Hong, MJ Ahn, WQ Chong… - Annals of …, 2023 - Elsevier
Background Pembrolizumab previously demonstrated robust antitumor activity and
manageable safety in a phase Ib study of patients with heavily pretreated, programmed …

Immunotherapy for nasopharyngeal carcinoma: Current status and prospects

H Huang, Y Yao, X Deng, Z Huang… - International …, 2023 - spandidos-publications.com
Nasopharyngeal carcinoma (NPC) is an epithelial tumor located in the nasopharynx and is
highly associated with Epstein‑Barr virus (EBV) infection. Although radiotherapy alone can …

Effect of induction chemotherapy with paclitaxel, cisplatin, and capecitabine vs cisplatin and fluorouracil on failure-free survival for patients with stage IVA to IVB …

WZ Li, X Lv, D Hu, SH Lv, GY Liu, H Liang, YF Ye… - JAMA …, 2022 - jamanetwork.com
Importance Induction chemotherapy added to concurrent chemoradiotherapy significantly
improves survival for patients with locoregionally advanced nasopharyngeal carcinoma, but …

Effect of capecitabine maintenance therapy plus best supportive care vs best supportive care alone on progression-free survival among patients with newly diagnosed …

GY Liu, WZ Li, DS Wang, H Liang, X Lv, YF Ye… - JAMA …, 2022 - jamanetwork.com
Importance Capecitabine maintenance therapy improves survival outcomes in various
cancer types, but data are limited on the efficacy and safety of capecitabine maintenance …