Multifarious roles of sialic acids in immunity
Sialic acids are a diverse family of monosaccharides widely expressed on all cell surfaces of
vertebrates and so‐called “higher” invertebrates, and on certain bacteria that interact with …
vertebrates and so‐called “higher” invertebrates, and on certain bacteria that interact with …
Glycome dynamics in T and B cell development: basic immunological mechanisms and clinical applications
Glycans cover the surfaces of all mammalian cells through a process called glycosylation.
Nearly all proteins and receptors that integrate the intricate series of co-stimulatory/inhibitory …
Nearly all proteins and receptors that integrate the intricate series of co-stimulatory/inhibitory …
Polysialic acid: Biosynthesis, novel functions and applications
KJ Colley, K Kitajima, C Sato - Critical reviews in biochemistry and …, 2014 - Taylor & Francis
As an anti-adhesive, a reservoir for key biological molecules, and a modulator of signaling,
polysialic acid (polySia) is critical for nervous system development and maintenance …
polysialic acid (polySia) is critical for nervous system development and maintenance …
Disialic, oligosialic and polysialic acids: distribution, functions and related disease
C Sato, K Kitajima - The journal of biochemistry, 2013 - academic.oup.com
Sialic acids (Sia) are involved in many biological activities and frequently exist as monosialyl
residues at the non-reducing terminal end of glycoconjugates. Occasionally, polymerized …
residues at the non-reducing terminal end of glycoconjugates. Occasionally, polymerized …
Added prognostic value of secondary AML-like gene mutations in ELN intermediate-risk older AML: ALFA-1200 study results
C Gardin, C Pautas, E Fournier, R Itzykson… - Blood …, 2020 - ashpublications.org
In this study, we aimed to refine prognostication of older with acute myeloid leukemia (AML)
after intensive chemotherapy. Five hundred and nine patients aged 60 years or older …
after intensive chemotherapy. Five hundred and nine patients aged 60 years or older …
Glycans as shapers of tumour microenvironment: a sweet driver of T‐cell‐mediated anti‐tumour immune response
A Fernandes, CM Azevedo, MC Silva, G Faria… - …, 2023 - Wiley Online Library
Essentially all cells are covered with a dense coat of different glycan structures/sugar chains,
giving rise to the so‐called glycocalyx. Changes in cellular glycosylation are a hallmark of …
giving rise to the so‐called glycocalyx. Changes in cellular glycosylation are a hallmark of …
Hematopoietic progenitor migration to the adult thymus
DA Zlotoff, A Bhandoola - Annals of the New York Academy of …, 2011 - Wiley Online Library
Although most hematopoietic lineages develop in the bone marrow (BM), T cells uniquely
complete their development in the specialized environment of the thymus. Hematopoietic …
complete their development in the specialized environment of the thymus. Hematopoietic …
Polysialic acid in the immune system
TM Villanueva-Cabello… - Frontiers in …, 2022 - frontiersin.org
Polysialic acid (polySia) is a highly regulated polymer of sialic acid (Sia) with such potent
biophysical characteristics that when expressed drastically influences the interaction …
biophysical characteristics that when expressed drastically influences the interaction …
Role of neuropilin-2 in the immune system
S Schellenburg, A Schulz, DM Poitz, MH Muders - Molecular Immunology, 2017 - Elsevier
Neuropilins (NRPs) are single transmembrane receptors with short cytoplasmic tails and are
dependent on receptors like VEGF receptors or Plexins for signal transduction. NRPs are …
dependent on receptors like VEGF receptors or Plexins for signal transduction. NRPs are …
Multiple roles of glycans in hematological malignancies
The three types of blood cells (red blood cells for carrying oxygen, white blood cells for
immune protection, and platelets for wound clotting) arise from hematopoietic …
immune protection, and platelets for wound clotting) arise from hematopoietic …