Microneedle for transdermal drug delivery: current trends and fabrication

JH Jung, SG Jin - Journal of pharmaceutical investigation, 2021 - Springer
Background Transdermal delivery has the advantage of bypassing the first-pass effect and
allowing sustained release of the drug. However, the drug delivery is limited owing to the …

Hydrogel‐forming microneedles: current advancements and future trends

JG Turner, LR White, P Estrela… - Macromolecular …, 2021 - Wiley Online Library
In this focused progress review, the recent developments and trends of hydrogel‐forming
microneedles (HFMs) and potential future directions are presented. Previously …

Microneedle patch for the ultrasensitive quantification of protein biomarkers in interstitial fluid

Z Wang, J Luan, A Seth, L Liu, M You, P Gupta… - Nature Biomedical …, 2021 - nature.com
The detection and quantification of protein biomarkers in interstitial fluid is hampered by
challenges in its sampling and analysis. Here we report the use of a microneedle patch for …

Lab under the skin: microneedle based wearable devices

H Teymourian, F Tehrani, K Mahato… - Advanced healthcare …, 2021 - Wiley Online Library
While the current smartwatches and cellphones can readily track mobility and vital signs, a
new generation of wearable devices is rapidly developing to enable users to monitor their …

Microneedles in drug delivery: progress and challenges

M Avcil, A Çelik - Micromachines, 2021 - mdpi.com
In recent years, an innovative transdermal delivery technology has attracted great interest for
its ability to distribute therapeutics and cosmeceuticals for several applications, including …

Microneedle array encapsulated with programmed DNA hydrogels for rapidly sampling and sensitively sensing of specific microRNA in dermal interstitial fluid

Q Yang, Y Wang, T Liu, C Wu, J Li, J Cheng, W Wei… - ACS …, 2022 - ACS Publications
Author: Please verify that the changes made to improve the English still retain your original
meaning. Detection of microRNA (miRNA) in dermal interstitial fluid (ISF) has emerged as …

Wearable microneedle array-based sensor for transdermal monitoring of pH levels in interstitial fluid

M Dervisevic, E Dervisevic, L Esser, CD Easton… - Biosensors and …, 2023 - Elsevier
Microneedle-based wearable sensors offer an alternative approach to traditional invasive
blood-based health monitoring and disease diagnostics techniques. Instead of blood …

Design principles of microneedles for drug delivery and sampling applications

Z Le, J Yu, YJ Quek, B Bai, X Li, Y Shou, B Myint, C Xu… - Materials Today, 2023 - Elsevier
Microneedles technology is a powerful platform to achieve efficient transdermal delivery of
bioactive molecules for local or systemic therapies attributing to their minimally invasive …

Wearable Clinic: From Microneedle‐Based Sensors to Next‐Generation Healthcare Platforms

H Sun, Y Zheng, G Shi, H Haick, M Zhang - Small, 2023 - Wiley Online Library
The rapid development of wearable biosensing calls for next‐generation devices that allow
continuous, real‐time, and painless monitoring of health status along with responsive …

A hydrogel microneedle patch for point‐of‐care testing based on skin interstitial fluid

R He, Y Niu, Z Li, A Li, H Yang, F Xu… - Advanced Healthcare …, 2020 - Wiley Online Library
Skin interstitial fluid (ISF) holds great potential as a highly desirable sample resource for
point‐of‐care testing (POCT), where the key is to effectively collect target biomarkers from …