[HTML][HTML] Radix Paeoniae Alba attenuates Radix Bupleuri-induced hepatotoxicity by modulating gut microbiota to alleviate the inhibition of saikosaponins on …

C Chen, W Gong, J Tian, X Gao, X Qin, G Du… - Journal of …, 2023 - Elsevier
Radix Bupleuri (RB) is commonly used to treat depression, but it can also lead to
hepatotoxicity after long-term use. In many anti-depression prescriptions, RB is often used in …

Response of lipid metabolism, energy supply, and cell fate in yellowstripe goby (Mugilogobius chulae) exposed to environmentally relevant concentrations …

Y Zhao, C Duan, H Zhang, W Gong, Y Wang… - Environmental …, 2024 - Elsevier
The usage of typical pharmaceuticals and personal care products (PPCPs) such as
cardiovascular and lipid-modulating drugs in clinical care accounts for the largest share of …

[HTML][HTML] Metabolic characteristics of evodiamine were associated with its hepatotoxicity via PPAR/PI3K/AKT/NF-кB/tight junction pathway-mediated apoptosis in …

Q Fan, R Liang, M Chen, Z Li, X Tao, H Ren… - Ecotoxicology and …, 2024 - Elsevier
Evodiae Fructus (EF), an herbal medicine, possesses remarkable anti-inflammatory and
analgesic properties. It exhibits insecticidal activity as a potent insecticide candidate …

Investigation of the applicability of the zebrafish model for the evaluation of aristolochic acid-related nephrotoxicity

C Meilin, Z Chongjun, LI Zhiqi, FAN Qiqi, LU Shan… - Phytomedicine, 2023 - Elsevier
Background The risk of compounds/drugs, including aristolochic acid-induced nephrotoxicity
remains high and is a significant public health concern. Therefore, it is particularly important …