Physiological evidence supporting the role of the adenine nucleotide, ATP 1 (Figure 1), as a
neurotransmitter was first summarized in detail in 1972, 1 representing the basis of …

Background and purpose: Inhibitory junction potentials (IJP) are responsible for smooth
muscle relaxation in the gastrointestinal tract. The aim of this study was to pharmacologically …

Preference for the Northern (N) ring conformation of the ribose moiety of nucleotide 5 '-
triphosphate agonists at P2Y1, P2Y2, P2Y4, and P2Y11 receptors, but not P2Y6 receptors …

Platelets possess three P2 receptors: two (P2Y 1 and P2Y 12) are receptors for ADP, and
one (P2X 1) is a receptor for ATP. P2Y 1, a Gq-coupled receptor, is responsible for …

Purinergic inhibitory neuromuscular transmission plays an important role in the control of
intestinal motility. In most tissues this neurotransmission is apamin-sensitive, but recent …

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___________________________________________________________________________Index …

Hiermit erkläre ich an Eides statt, dass ich die Dissertation „β-Arrestin/Rezeptor-
Interaktionen “selbstständig angefertigt habe und keine anderen als die von mir …

Extracellular purine and pyrimidine nucleosides and nucleotides stimulate signalling
responses via a family of G protein-coupled receptors (GPCR), known as purinergic …

Die Bedeutung der β-Arrestine als multifunktionelle Adapterproteine GPCR-vermittelter
Signaltransduktion hat in den letzten Jahren immer mehr zugenommen. In der vorliegenden …

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