Discovery of potential biomarkers for osteoporosis diagnosis by individual omics and multi-omics technologies

J Yang, J Wu - Expert Review of Molecular Diagnostics, 2023 - Taylor & Francis
Introduction Global aging has made osteoporosis an increasingly serious public health
problem. Osteoporotic fractures seriously affect the quality of life of patients and increase …

Role and Regulation of Transcription Factors in Osteoclastogenesis

T Jiang, T Xia, F Qiao, N Wang, Y Jiang… - International Journal of …, 2023 - mdpi.com
Bones serve mechanical and defensive functions, as well as regulating the balance of
calcium ions and housing bone marrow.. The qualities of bones do not remain constant …

Bioactive composite hydrogel with effects of robust promoting osteogenesis and immunomodulation for osteoporotic bone regeneration

B Sun, H Wang, B Xiao, H Yan, H Wu, R Zhang… - Chemical Engineering …, 2023 - Elsevier
Osteoporotic bone defect is an intractable challenge in clinical practice, involving impaired
bone repair ability and abnormal immune response. Despite the development of various …

Heterogeneous osteoimmune profiles via single-cell transcriptomics in osteoporotic patients who fail bisphosphonate treatment

BR Keum, HJ Kim, J Lee, M Lee… - Proceedings of the …, 2024 - National Acad Sciences
Postmenopausal osteoporosis arises from imbalanced osteoclast and osteoblast activity,
and mounting evidence suggests a role for the osteoimmune system in bone homeostasis …

发育性颈椎管狭窄人群血清差异蛋白质组学分析

卜献忠, 钟远鸣, 卜保献, 李记天, 汪利合, 李慧英… - 中国组织工程研究, 2024 - cjter.com
摘要背景: 正常健康人与发育性颈椎管狭窄(气虚血瘀证) 人群之间的血清特异性生物学标志物
尚未完全明确. 目的: 寻找并鉴定气虚血瘀证发育性颈椎管狭窄的潜在生物学标志物. 方法 …

Serum differential proteomic analysis of developmental cervical canal stenosis

X Bu, Y Zhong, B Bu, J Li, L Wang, H Li, H Yang… - Chinese Journal of …, 2024 - cjter.com
BACKGROUND: Serum-specific biomarkers between normal healthy individuals and
populations with developmental cervical canal stenosis (Qi deficiency and blood stasis …

Screening of molecular markers associated with hornless traits in Qira black sheep

W Zhou, X Li, X Zhang, Z Han, Y Peng, X Bai, R Yang… - 2024 - researchsquare.com
Hornless trait in sheep is one of the important traits affecting their economic production
efficiency. In order to screen the molecular markers related to hornless trait in Qira black …

Study on the association of the microstructure and bone metabolism in the osteoporotic femoral head

C Wang, P Wang, F Li, Y Li, M Zhao, H Feng… - Molecular Biology …, 2023 - Springer
Background We compared the bone microstructure and metabolism of the femoral heads in
patients with osteoporosis (OP) and non-OP patients to investigate the pathologic …