Discovery of natural anti-inflammatory alkaloids: Potential leads for the drug discovery for the treatment of inflammation

R Bai, C Yao, Z Zhong, J Ge, Z Bai, X Ye, T Xie… - European Journal of …, 2021 - Elsevier
Inflammation is an adaptive response of the immune system to tissue malfunction or
homeostatic imbalance. Corticosteroids and non-steroidal anti-inflammatory drugs (NSAIDs) …

[HTML][HTML] Genus Sophora: a comprehensive review on secondary chemical metabolites and their biological aspects from past achievements to future perspectives

HI Abd-Alla, D Souguir, MO Radwan - Archives of pharmacal research, 2021 - Springer
Sophora is deemed as one of the most remarkable genera of Fabaceae, and the third
largest family of flowering plants. The genus Sophora comprises approximately 52 species …

[HTML][HTML] Alkaloids: therapeutic potential against human coronaviruses

BC Fielding, C da Silva Maia Bezerra Filho, NSM Ismail… - Molecules, 2020 - mdpi.com
Alkaloids are a class of natural products known to have wide pharmacological activity and
have great potential for the development of new drugs to treat a wide array of pathologies …

[HTML][HTML] An ethnoveterinary study on medicinal plants used by the Buyi people in Southwest Guizhou, China

Y Xiong, C Long - Journal of ethnobiology and ethnomedicine, 2020 - Springer
Abstract Background The Buyi (Bouyei) people in Qianxinan Buyi and Miao Autonomous
Prefecture, Southwest Guizhou, China, have used medicinal plants and traditional remedies …

[HTML][HTML] Characterization of Volatile Organic Compounds Emitted from Endophytic Burkholderia cenocepacia ETR-B22 by SPME-GC-MS and Their Inhibitory Activity …

JH Chen, W Xiang, KX Cao, X Lu, SC Yao, D Hung… - Molecules, 2020 - mdpi.com
The use of antagonistic microorganisms and their volatile organic compounds (VOCs) to
control plant fungal pathogens is an eco-friendly and promising substitute for chemical …

Quinolizidine-type alkaloids: chemodiversity, occurrence, and bioactivity

W Cely-Veloza, MJ Kato, E Coy-Barrera - ACS omega, 2023 - ACS Publications
Quinolizidine alkaloids (QAs) are nitrogen-containing compounds produced naturally as
specialized metabolites distributed in plants and animals (eg, frogs, sponges). The present …

[HTML][HTML] Targeting natural products against SARS-CoV-2

A Al-Harrasi, T Behl, T Upadhyay, S Chigurupati… - … Science and Pollution …, 2022 - Springer
The human coronavirus disease (COVID-19) pandemic is caused by a novel coronavirus;
the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2). Natural products …

The biological activities of quinolizidine alkaloids

J Zhang, YQ Liu, J Fang - The Alkaloids: Chemistry and Biology, 2023 - Elsevier
Quinolizidine alkaloids isolated from various marine and terrestrial animals and plants are
primarily composed of lupinine-, matrine-, and sparteine-type alkaloids. Matrine …

Quinolizidine alkaloids from Sophora alopecuroides with anti-inflammatory and anti-tumor properties

JC Li, WF Dai, D Liu, ZJ Zhang, MY Jiang, KR Rao… - Bioorganic …, 2021 - Elsevier
Abstract Forty-three quinolizidine alkaloids (1–43), including twelve new matrine-type ones,
sophalodes A–L (1–7, 17, 19 and 28–30), were isolated from the seeds of Sophora …

Quinolizidine alkaloids from the roots of Sophora flavescens

JC Li, ZJ Zhang, D Liu, MY Jiang, RT Li… - Natural Product …, 2022 - Taylor & Francis
Seventeen quinolizidine alkaloids, including a new matrine-type one, sophcence A (1), were
isolated from the roots of Sophora flavescens Alt. The structure of compound 1 was …