Comparison of first-line with second-line antibiotics for acute exacerbations of chronic bronchitis: a metaanalysis of randomized controlled trials

G Dimopoulos, II Siempos, IP Korbila, KG Manta… - Chest, 2007 - Elsevier
Background Although acute exacerbations of chronic bronchitis (AECBs) are common, there
has been no metaanalysis that focused on the optimum regimen. Methods To evaluate the …

Haemophilus haemolyticus: A Human Respiratory Tract Commensal to Be Distinguished from Haemophilus influenzae

TF Murphy, AL Brauer, S Sethi, M Kilian… - The Journal of …, 2007 - academic.oup.com
Background Haemophilus influenzae is a common pathogen in adults with chronic
obstructive pulmonary disease (COPD). In a prospective study, selected isolates of apparent …

Antimicrobial treatment of lower respiratory tract infections in the hospital setting

RF Grossman, JC Rotschafer, JS Tan - The American journal of medicine, 2005 - Elsevier
Respiratory tract infections (RTIs) that may require hospitalization include acute
exacerbations of chronic bronchitis (AECB), community-acquired pneumonia (CAP), and …

Are Broad-Spectrum Fluoroquinolones More Likely To Cause Clostridium difficile-Associated Disease?

IA Dhalla, MM Mamdani, AE Simor… - Antimicrobial agents …, 2006 - Am Soc Microbiol
Limited evidence suggests that broad-spectrum fluoroquinolones such as gatifloxacin and
moxifloxacin are more likely to cause Clostridium difficile-associated disease than …

Aerosolized fluoroquinolones and uses thereof

MW Surber, KA Bostian, MN Dudley… - US Patent …, 2010 - Google Patents
Disclosed herein are formulations of fluoroquinolones suitable for aerosolization and use of
such formulations for aerosol administration of fluoroquinolone antimicrobials for the …

Cefditoren versus levofloxacin in patients with exacerbations of chronic bronchitis: serum inflammatory biomarkers, clinical efficacy, and microbiological eradication

F Blasi, P Tarsia, M Mantero… - … and clinical risk …, 2013 - Taylor & Francis
Background The aim of this open-label, randomized, parallel-group pilot study was to
evaluate the efficacy of cefditoren pivoxil and levofloxacin in terms of speed of reduction in …

[HTML][HTML] Short-course fluoroquinolone therapy in exacerbations of chronic bronchitis and COPD

A Anzueto, M Miravitlles - Respiratory medicine, 2010 - Elsevier
Acute exacerbations of chronic bronchitis (AECB) and chronic obstructive pulmonary
disease (COPD) are associated with significant healthcare costs and contribute to the …

Activity of moxifloxacin on biofilms produced in vitro by bacterial pathogens involved in acute exacerbations of chronic bronchitis

S Roveta, AM Schito, A Marchese, GC Schito - International journal of …, 2007 - Elsevier
The aim of this study was to assess whether moxifloxacin is able to inhibit the synthesis of
and to disrupt biofilms produced in vitro by bacterial pathogens involved in acute bacterial …

Gatifloxacin biodegradable implant for treatment of experimental osteomyelitis: in vitro and in vivo evaluation

AH El-Kamel, MM Baddour - Drug delivery, 2007 - Taylor & Francis
Osteomyelitis is an inflammatory bone disease caused by pyogenic bacteria. The
advantages of localized biodegradable therapy for osteomyelitis include high local antibiotic …

Pharmacoeconomics of the management of acute exacerbations of chronic obstructive pulmonary disease

S Simoens, M Decramer - Expert opinion on pharmacotherapy, 2007 - Taylor & Francis
Acute exacerbations of chronic obstructive pulmonary disease (COPD) impose a significant
burden on society in terms of morbidity, mortality, reduced quality of life and healthcare …