Management of moderate to severe traumatic brain injury: an update for the intensivist

G Meyfroidt, P Bouzat, MP Casaer, R Chesnut… - Intensive care …, 2022 - Springer
Traumatic brain injury (TBI) remains one of the most fatal and debilitating conditions in the
world. Current clinical management in severe TBI patients is mainly concerned with …

[HTML][HTML] Cerebral pressure autoregulation in brain injury and disorders–a review on monitoring, management, and future directions

TS Wettervik, M Fahlström, P Enblad, A Lewén - World neurosurgery, 2022 - Elsevier
The role of cerebral pressure autoregulation (CPA) in brain injury and disorders has gained
increased interest. The CPA is often disturbed as a consequence of acute brain injury, which …

Ephedrine versus Phenylephrine Effect on Cerebral Blood Flow and Oxygen Consumption in Anesthetized Brain Tumor Patients: A Randomized Clinical Trial

KU Koch, IK Mikkelsen, J Aanerud, US Espelund… - …, 2020 - pubs.asahq.org
Background Studies in anesthetized patients suggest that phenylephrine reduces regional
cerebral oxygen saturation compared with ephedrine. The present study aimed to quantify …

[PDF][PDF] Optimizing Traumatic Brain Injury Management: A Multidisciplinary Approach and Lessons Learned from a Complex Case

I Karunarathna, K Kusumarathna… - Uva Clinical Lab …, 2024 - researchgate.net
strategies to optimize patient outcomes. We present a case of a 32-year-old male who
suffered severe TBI following a motorcycle accident, emphasizing the complexity and …

[HTML][HTML] Intelligent prediction of RBC demand in trauma patients using decision tree methods

YN Feng, ZH Xu, JT Liu, XL Sun, DQ Wang… - Military Medical …, 2021 - Springer
Background The vital signs of trauma patients are complex and changeable, and the
prediction of blood transfusion demand mainly depends on doctors' experience and trauma …

Effects of anesthetic agents and other drugs on cerebral blood flow, metabolism, and intracranial pressure

M Matsumoto, A Yamashita - Cottrell & Patel's Neuroanesthesia, 2025 - Elsevier
Major goals in neurosurgical anesthesia are to provide adequate tissue perfusion to the
brain (and spinal cord) so that the regional metabolic demand is met and to provide …

Effects of ephedrine and phenylephrine on cerebral oxygenation: observational prospective study using near-infrared time-resolved spectroscopy

Y Kubo, T Kubo, T Toki, I Yokota, Y Morimoto - Journal of Clinical …, 2023 - Springer
It has been reported that cerebral oxygenation (ScO2) measured by near infrared
spectroscopy is maintained or increased by treatment with ephedrine, whereas almost all …

Immediate postoperative electroencephalography monitoring in pediatric moyamoya disease and syndrome

AL Huguenard, RM Guerriero, SR Tomko… - Pediatric Neurology, 2021 - Elsevier
Background Moyamoya disease and syndrome are progressive steno-occlusive
cerebrovascular diseases that manifest clinically with ischemic episodes. There is evidence …

Early vasopressor utilization strategies and outcomes in critically ill patients with severe traumatic brain injury

C Toro, T Ohnuma, J Komisarow… - Anesthesia & …, 2022 - journals.lww.com
BACKGROUND: Early hypotension after severe traumatic brain injury (sTBI) is associated
with increased mortality and poor long-term outcomes. Current guidelines suggest the use of …

Association of vasopressor choice with clinical and functional outcomes following moderate to severe traumatic brain injury: a TRACK-TBI study

C Toro, N Temkin, J Barber, G Manley, S Jain… - Neurocritical care, 2022 - Springer
Background Early hypotension following moderate to severe traumatic brain injury (TBI) is
associated with increased mortality and poor long-term outcomes. Current guidelines …