Brain aging is a complex process that affects everything from the subcellular to the organ
level, begins early in life, and accelerates with age. Morphologically, brain aging is primarily …

Over the past decade, in-vivo MRI studies have provided many invaluable insights into the
neural substrates underlying autism spectrum disorder (ASD), which is now known to be …

The rapid growth of the human cortex during development is accompanied by the folding of
the brain into a highly convoluted structure,,. Recent studies have focused on the genetic …

The size and extent of folding of the mammalian cerebral cortex are important factors that
influence a species' cognitive abilities and sensorimotor skills. Studies in various animal …

The human brain is the continuous subject of extensive investigation aimed at
understanding its behavior and function. Despite a clear evidence that mechanical factors …

The exterior of the mammalian brain—the cerebral cortex—has a conserved layered
structure whose thickness varies little across species. However, selection pressures over …

Neurodevelopment is a complex, dynamic process that involves a precisely orchestrated
sequence of genetic, environmental, biochemical, and physical events. Developmental …

Cortical folding is a hallmark of many, but not all, mammalian brains. The degree of folding
increases with brain size across mammals, but at different scales between orders and …

The cerebral cortex of large mammals undergoes massive surface area expansion and
folding during development. Specific mechanisms to orchestrate the growth of the cortex in …

Many structural features of the mammalian central nervous system can be explained by a
morphogenetic mechanism that involves mechanical tension along axons, dendrites and …