Surgery is a mainstay treatment for patients with solid tumours. However, despite surgical
resection with a curative intent and numerous advances in the effectiveness of (neo) …

Colorectal cancer (CRC) is one of the most frequent gastrointestinal malignancies that are
considered as a global health challenge. Despite many progresses in therapeutic methods …

Poorly controlled postoperative pain is associated with increased morbidity, negatively
affects quality of life and functional recovery, and is a risk factor for persistent pain and …

Background The relationship between surgery and anesthetic-induced immunosuppression
and cancer recurrence remains unresolved. Surgery and anesthesia stimulate the …

In patients with cancer, opioids are principally used for the management of acute surgical
and chronic cancer‐related pain. However, opioids have many non‐analgesic effects …

Cancer is a leading cause of morbidity and mortality worldwide and the ratio of incidence is
increasing. Mortality usually results from recurrence or metastases. Surgical removal of the …

Background Animal models and retrospective clinical data suggest that certain anaesthetic
techniques can attenuate immunosuppression and minimize metastasis after cancer …

Purpose Mortality among cancer patients is more commonly due to the effects of metastasis
and recurrence as opposed to the primary tumour. Various perioperative factors have been …

Recent epidemiologic studies implying differences in cancer recurrence based on
anesthetic regimens raise the possibility that the mu opioid receptor (MOR) can influence …

Background Morphine stimulates angiogenesis and cancer progression in mice. We
investigated whether morphine influences tumour onset, development, and animal model …