The amide functional group plays a key role in the composition of biomolecules, including
many clinically approved drugs. Bioisosterism is widely employed in the rational …

Urea and thiourea represent privileged structures in medicinal chemistry. Indeed, these
moieties constitute a common framework of a variety of drugs and bioactive compounds …

Parallel library synthesis is an important tool for drug discovery because it enables the
synthesis of closely related analogues in parallel via robust and general synthetic …

A copper‐catalyzed atroposelective ring‐opening reaction of cyclic diaryliodoniums, sodium
cyanate (NaOCN) and phenols is reported. The reaction chemoselectively affords axially …

Carbon-14 (14C) is a gold standard technology routinely utilized in pharmaceutical and
agrochemical industries for tracking synthetic organic molecules and providing their …

We report the mild activation of carbamoyl azides to the corresponding nitrenes using a blue
light/[Ir]-catalyzed strategy, which enables stereospecific access to N-trifluoromethyl …

The photoelectrochemical reduction of CO 2 and N 2 (N 2 CO 2 RR) is a promising method
of producing urea under ambient conditions since highly active and stable electrocatalysts …

The development of new small molecules from known structural motifs through molecular
hybridization is one of the trends in drug discovery. In this connection, we have combined …

Due to their very good chemical and proteolytic stability, ability to penetrate cell membranes,
and resemblance to a peptide bond, carbamate derivatives have received much attention in …

In this work, synthesis, and crystal structure of molecule 2-amino-4′-fluorobenzophenone
(FAB) is confirmed by using FT-IR, FT-Raman, 1 H and 13 C NMR chemical shifts, compared …