Cyclin B2 (CCNB2) Stimulates the Proliferation of Triple‐Negative Breast Cancer (TNBC) Cells In Vitro and In Vivo
S Wu, R Su, H Jia - Disease markers, 2021 - Wiley Online Library
Triple‐negative breast cancer (TNBC) is the most aggressive type of breast cancer.
Currently, targeting therapy makes great advances for the treatment of TNBC, whereas more …
Currently, targeting therapy makes great advances for the treatment of TNBC, whereas more …
[HTML][HTML] Genomic Landscape of Normal and Breast Cancer Tissues in a Hungarian Pilot Cohort
A limited number of studies have focused on the mutational landscape of breast cancer in
different ethnic populations within Europe and compared the data with other ethnic groups …
different ethnic populations within Europe and compared the data with other ethnic groups …
Prevalence and spectrum of pathogenic germline variants in intestinal and pancreatobiliary type of ampullary cancer
Background Ampullary cancer may occur as a component of hereditary cancer syndromes.
Mutations in inherited cancer susceptibility genes play a therapeutic role and its knowledge …
Mutations in inherited cancer susceptibility genes play a therapeutic role and its knowledge …
[HTML][HTML] An integrated somatic and germline approach to aid interpretation of germline variants of uncertain significance in cancer susceptibility genes
A Schwartz, DK Manning, DR Koeller… - Frontiers in …, 2022 - frontiersin.org
Genomic profiles of tumors are often unique and represent characteristic mutational
signatures defined by DNA damage or DNA repair response processes. The tumor-derived …
signatures defined by DNA damage or DNA repair response processes. The tumor-derived …
Application areas of traditional molecular genetic methods and NGS in relation to hereditary urological cancer diagnosis
DS Mikhaylenko, AS Tanas, DV Zaletaev… - Journal of …, 2020 - Wiley Online Library
Next generation sequencing (NGS) is widely used for diagnosing hereditary cancer
syndromes. Often, exome sequencing and extended gene panel approaches are the only …
syndromes. Often, exome sequencing and extended gene panel approaches are the only …
[HTML][HTML] Non-BRCA1/BRCA2 high-risk familial breast cancers are not associated with a high prevalence of BRCAness
LB Andersen, MJ Larsen, H Davies, A Degasperi… - Breast Cancer …, 2023 - Springer
Background Familial breast cancer is in most cases unexplained due to the lack of
identifiable pathogenic variants in the BRCA1 and BRCA2 genes. The somatic mutational …
identifiable pathogenic variants in the BRCA1 and BRCA2 genes. The somatic mutational …
Validation of a NGS panel, with automated analysis, designed for detection of medically actionable tumor biomarkers for Latin America
M Salvo, E González-Feliú, J Toro, I Gallegos… - medRxiv, 2021 - medrxiv.org
The genomic characterization of solid tumors and a rapidly growing repertoire of target
drugs are revolutionizing cancer treatment. Next-generation sequencing (NGS) panels are …
drugs are revolutionizing cancer treatment. Next-generation sequencing (NGS) panels are …