Antimicrobial peptides are small molecules with activity against bacteria, yeasts, fungi,
viruses, bacteria, and even tumor cells that make these molecules attractive as therapeutic …

Plant defensins are small, cysteine-rich peptides that possess biological activity towards a
broad range of organisms. Their activity is primarily directed against fungi, but bactericidal …

Infectious diseases caused by bacteria, viruses or fungi are among the leading causes of
death worldwide. The emergence of drug-resistance mechanisms, especially among …

In the last decades, the indiscriminate use of conventional antibiotics has generated high
rates of microbial resistance. This situation has increased the need for obtaining new …

Defensins are moonlighting peptides which are broadly distributed throughout all the living
kingdoms. They play a multitude of important roles in human health and disease …

Abstract NZ17074 (N1), an arenicin-3 derivative isolated from the lugworm, has potent
antibacterial activity and is cytotoxic. To reduce its cytotoxicity, seven N1 analogues with …

An infectious process into the uterine cavity represents a major endangered condition that
compromises the immune privilege of the maternal–fetal unit and increases the risk for …

When pulp tissue is damaged by caries or trauma, vital pulp therapy (VPT) can help
preserve the pulp tissue for long-term retention of teeth. However, the choice of pulp capping …

Invasive fungal infections caused by opportunistic fungal pathogens are associated with
high mortality rates, mainly due to the occurrence of genotypic and/or phenotypic resistance …

Human defensins play multiple roles in innate immunity including direct antimicrobial killing
and immunomodulatory activity. They have three disulfide bridges which contribute to the …