[HTML][HTML] Regulation of lncRNA and its role in cancer metastasis

J Li, H Meng, Y Bai, K Wang - Oncology research, 2016 - ncbi.nlm.nih.gov
Metastasis is the primary cause of cancer-related death all over the world. Metastasis is a
process by which cancer spreads from the place at which it first arose to distant locations in …

From junk to master regulators of invasion: lncRNA functions in migration, EMT and metastasis

S Dhamija, S Diederichs - International journal of cancer, 2016 - Wiley Online Library
Metastasis is a multistep process that involves the dissemination of cells from the primary
tumor and colonization of distant secondary organs. Epithelial cells at the invasive front of a …

The emerging role of long noncoding RNAs in human disease

JK DiStefano - Disease Gene Identification: Methods and Protocols, 2018 - Springer
Only a small fraction of the human genome corresponds to protein-coding genes.
Historically, the vast majority of genomic sequence was dismissed as transcriptionally silent …

Long noncoding RNAs in cancer: from function to translation

A Sahu, U Singhal, AM Chinnaiyan - Trends in cancer, 2015 - cell.com
While our understanding of the molecular mechanisms underlying cancer has significantly
improved, most of our knowledge focuses on protein-coding genes that make up a fraction of …

[HTML][HTML] Long non-coding RNAs in Oral squamous cell carcinoma: biologic function, mechanisms and clinical implications

L Zhang, X Meng, X Zhu, D Yang, R Chen, Y Jiang… - Molecular cancer, 2019 - Springer
There is growing evidence that regions of the genome that cannot encode proteins play an
important role in diseases. These regions are usually transcribed into long non-coding …

[HTML][HTML] LncRNA in tumorigenesis of non-small-cell lung cancer: From bench to bedside

Q Hu, H Ma, H Chen, Z Zhang, Q Xue - Cell death discovery, 2022 - nature.com
Lung cancer has been one of the leading causes of cancer-related death worldwide, and
non-small-cell lung cancer (NSCLC) accounts for the majority of lung cancer morbidity, yet …

Long noncoding RNA-MEG3 is involved in diabetes mellitus-related microvascular dysfunction

GZ Qiu, W Tian, HT Fu, CP Li, B Liu - Biochemical and biophysical research …, 2016 - Elsevier
Microvascular dysfunction is an important characteristic of diabetic retinopathy. Long non-
coding RNAs (lncRNAs) play important roles in diverse biological processes. In this study …

[HTML][HTML] MALAT1 promotes colorectal cancer cell proliferation/migration/invasion via PRKA kinase anchor protein 9

MH Yang, ZY Hu, C Xu, LY Xie, XY Wang… - … et Biophysica Acta (BBA …, 2015 - Elsevier
Our previous studies have shown that the 3′ end of metastasis associated lung
adenocarcinoma transcript 1 (MALAT1) is involved in colorectal cancer (CRC) cell …

[HTML][HTML] The Long Noncoding RNA MEG3 Contributes to Cisplatin Resistance of Human Lung Adenocarcinoma

J Liu, L Wan, K Lu, M Sun, X Pan, P Zhang, B Lu, G Liu… - PloS one, 2015 - journals.plos.org
Long noncoding RNAs (lncRNAs) have been identified as oncogenes or tumor suppressors
that are involved in tumorigenesis and chemotherapy drug resistance. Maternally expressed …

Circulating long noncoding RNA act as potential novel biomarkers for diagnosis and prognosis of non‐small cell lung cancer

Y Xie, Y Zhang, L Du, X Jiang, S Yan… - Molecular …, 2018 - Wiley Online Library
Lung cancer is the first leading cause of cancer deaths worldwide. Non‐small cell lung
cancer (NSCLC) is the most common type of lung cancer. Increasing evidence shows that …