[HTML][HTML] Inhibitory effects of long noncoding RNA MEG3 on hepatic stellate cells activation and liver fibrogenesis
Long noncoding RNAs (lncRNAs) are being increasingly recognized as major players in
governing fundamental biological processes through diverse mechanisms. Maternally …
governing fundamental biological processes through diverse mechanisms. Maternally …
Long noncoding RNA MEG3 activation of p53 mediates ischemic neuronal death in stroke
H Yan, J Yuan, L Gao, J Rao, J Hu - Neuroscience, 2016 - Elsevier
Abstract Maternally expressed gene 3 (MEG3) is suggested to function as a long non-coding
RNA (lncRNA) and to play roles in various human cancers. However, the functional …
RNA (lncRNA) and to play roles in various human cancers. However, the functional …
Long noncoding RNAs as new architects in cancer epigenetics, prognostic biomarkers, and potential therapeutic targets
D Meseure, K Drak Alsibai, A Nicolas… - BioMed research …, 2015 - Wiley Online Library
Recent advances in genome‐wide analysis have revealed that 66% of the genome is
actively transcribed into noncoding RNAs (ncRNAs) while less than 2% of the sequences …
actively transcribed into noncoding RNAs (ncRNAs) while less than 2% of the sequences …
Regulatory roles of long noncoding RNAs implicated in cancer hallmarks
Cancer cells acquire numerous biological properties (designated “cancer hallmarks”), such
as cell survival and energy metabolism, that facilitate tumor growth and metastatic …
as cell survival and energy metabolism, that facilitate tumor growth and metastatic …
[HTML][HTML] Close interactions between lncRNAs, lipid metabolism and ferroptosis in cancer
J Huang, J Wang, H He, Z Huang, S Wu… - … journal of biological …, 2021 - ncbi.nlm.nih.gov
Abnormal lipid metabolism including synthesis, uptake, modification, degradation and
transport has been considered a hallmark of malignant tumors and contributes to the supply …
transport has been considered a hallmark of malignant tumors and contributes to the supply …
LncRNA MEG3 downregulation mediated by DNMT3b contributes to nickel malignant transformation of human bronchial epithelial cells via modulating PHLPP1 …
C Zhou, C Huang, J Wang, H Huang, J Li, Q Xie, Y Liu… - Oncogene, 2017 - nature.com
Long noncoding RNAs (lncRNAs) are emerging as key factors in various fundamental
cellular biological processes, and many of them are likely to have functional roles in …
cellular biological processes, and many of them are likely to have functional roles in …
Emerging role of MicroRNAs and long noncoding RNAs in respiratory disease
R Booton, MA Lindsay - Chest, 2014 - Elsevier
The advent of techniques such as microarrays and high-throughput sequencing has
revolutionized our ability to examine messenger RNA (mRNA) expression within the …
revolutionized our ability to examine messenger RNA (mRNA) expression within the …
Expression and prognostic significance of lncRNA MALAT1 in pancreatic cancer tissues
JH Liu, G Chen, YW Dang, CJ Li… - Asian Pacific Journal of …, 2014 - koreascience.kr
Background: Long non-coding RNAs (lncRNAs) have been recently observed in various
human cancers. However, the role of lncRNAs in pancreatic duct adenocarcinoma (PDAC) …
human cancers. However, the role of lncRNAs in pancreatic duct adenocarcinoma (PDAC) …
[HTML][HTML] Potential applications of MEG3 in cancer diagnosis and prognosis
Y He, Y Luo, B Liang, L Ye, G Lu, W He - Oncotarget, 2017 - ncbi.nlm.nih.gov
LncRNAs are emerging as integral functional and regulatory components of normal
biological activities and are now considered as critically involved in the development of …
biological activities and are now considered as critically involved in the development of …
Overexpression of long non-coding RNA MEG3 suppresses breast cancer cell proliferation, invasion, and angiogenesis through AKT pathway
C Zhang, M Yu, X Li, Z Zhang, C Han… - Tumor Biology, 2017 - journals.sagepub.com
Long non-coding RNA MEG3 has been identified as a tumor suppressor which plays
important roles in tumorigenesis; however, its potential role in breast cancer has not been …
important roles in tumorigenesis; however, its potential role in breast cancer has not been …