[HTML][HTML] Inhibitory effects of long noncoding RNA MEG3 on hepatic stellate cells activation and liver fibrogenesis

Y He, Y Wu, C Huang, XM Meng, T Ma, BM Wu… - … et Biophysica Acta (BBA …, 2014 - Elsevier
Long noncoding RNAs (lncRNAs) are being increasingly recognized as major players in
governing fundamental biological processes through diverse mechanisms. Maternally …

Long noncoding RNA MEG3 activation of p53 mediates ischemic neuronal death in stroke

H Yan, J Yuan, L Gao, J Rao, J Hu - Neuroscience, 2016 - Elsevier
Abstract Maternally expressed gene 3 (MEG3) is suggested to function as a long non-coding
RNA (lncRNA) and to play roles in various human cancers. However, the functional …

Long noncoding RNAs as new architects in cancer epigenetics, prognostic biomarkers, and potential therapeutic targets

D Meseure, K Drak Alsibai, A Nicolas… - BioMed research …, 2015 - Wiley Online Library
Recent advances in genome‐wide analysis have revealed that 66% of the genome is
actively transcribed into noncoding RNAs (ncRNAs) while less than 2% of the sequences …

Regulatory roles of long noncoding RNAs implicated in cancer hallmarks

J Wang, X Zhang, W Chen, X Hu, J Li… - International journal of …, 2020 - Wiley Online Library
Cancer cells acquire numerous biological properties (designated “cancer hallmarks”), such
as cell survival and energy metabolism, that facilitate tumor growth and metastatic …

[HTML][HTML] Close interactions between lncRNAs, lipid metabolism and ferroptosis in cancer

J Huang, J Wang, H He, Z Huang, S Wu… - … journal of biological …, 2021 - ncbi.nlm.nih.gov
Abnormal lipid metabolism including synthesis, uptake, modification, degradation and
transport has been considered a hallmark of malignant tumors and contributes to the supply …

LncRNA MEG3 downregulation mediated by DNMT3b contributes to nickel malignant transformation of human bronchial epithelial cells via modulating PHLPP1 …

C Zhou, C Huang, J Wang, H Huang, J Li, Q Xie, Y Liu… - Oncogene, 2017 - nature.com
Long noncoding RNAs (lncRNAs) are emerging as key factors in various fundamental
cellular biological processes, and many of them are likely to have functional roles in …

Emerging role of MicroRNAs and long noncoding RNAs in respiratory disease

R Booton, MA Lindsay - Chest, 2014 - Elsevier
The advent of techniques such as microarrays and high-throughput sequencing has
revolutionized our ability to examine messenger RNA (mRNA) expression within the …

Expression and prognostic significance of lncRNA MALAT1 in pancreatic cancer tissues

JH Liu, G Chen, YW Dang, CJ Li… - Asian Pacific Journal of …, 2014 - koreascience.kr
Background: Long non-coding RNAs (lncRNAs) have been recently observed in various
human cancers. However, the role of lncRNAs in pancreatic duct adenocarcinoma (PDAC) …

[HTML][HTML] Potential applications of MEG3 in cancer diagnosis and prognosis

Y He, Y Luo, B Liang, L Ye, G Lu, W He - Oncotarget, 2017 - ncbi.nlm.nih.gov
LncRNAs are emerging as integral functional and regulatory components of normal
biological activities and are now considered as critically involved in the development of …

Overexpression of long non-coding RNA MEG3 suppresses breast cancer cell proliferation, invasion, and angiogenesis through AKT pathway

C Zhang, M Yu, X Li, Z Zhang, C Han… - Tumor Biology, 2017 - journals.sagepub.com
Long non-coding RNA MEG3 has been identified as a tumor suppressor which plays
important roles in tumorigenesis; however, its potential role in breast cancer has not been …