Aberrant methylation-mediated silencing of lncRNA MEG3 functions as a ceRNA in esophageal cancer

Z Dong, A Zhang, S Liu, F Lu, Y Guo, G Zhang… - Molecular Cancer …, 2017 - AACR
Abstract Maternally expressed gene 3 (MEG3), a long non-coding RNA (lncRNA), has tumor-
suppressor properties and its expression is lost in several human tumors. However, its …

LncRNA MEG3 enhances cisplatin sensitivity in non-small cell lung cancer by regulating miR-21-5p/SOX7 axis

P Wang, D Chen, H Ma, Y Li - OncoTargets and therapy, 2017 - Taylor & Francis
Background Long noncoding RNAs (lncRNAs) have been revealed to play essential role in
drug resistance of multiple cancers. LncRNA MEG3 was previously reported to be …

Non-small cell lung cancer: Emerging molecular targeted and immunotherapeutic agents

T Singh, MF Hassanabad, AF Hassanabad - Biochimica et Biophysica Acta …, 2021 - Elsevier
Non-small cell lung cancer (NSCLC) represents the most common and fatal type of primary
lung malignancies. NSCLC is often diagnosed at later stages and requires systemic …

miR‐193b availability is antagonized by Lnc RNA‐SNHG 7 for FAIM 2‐induced tumour progression in non‐small cell lung cancer

K She, H Yan, J Huang, H Zhou, J He - Cell proliferation, 2018 - Wiley Online Library
Objectives Long non‐coding RNA s have identified to involve into the tumour cell
proliferation, apoptosis and metastasis. We previously found that up‐regulated Lnc RNA …

The aberrant expression of MEG3 regulated by UHRF1 predicts the prognosis of hepatocellular carcinoma

H Zhuo, J Tang, Z Lin, R Jiang, X Zhang… - Molecular …, 2016 - Wiley Online Library
MEG3 as a tumor suppressor has been reported to be linked with pathogenesis of
malignancies including hepatocellular carcinoma (HCC). However, the mechanism of MEG3 …

Long non‐coding RNAs in non‐small cell lung cancer as biomarkers and therapeutic targets

J Chen, R Wang, K Zhang… - Journal of cellular and …, 2014 - Wiley Online Library
Lung cancer‐associated mortality is the most common cause of cancer death worldwide.
Non‐coding RNA s (nc RNA s), with no protein‐coding ability, have multiple biological roles …

[HTML][HTML] LncRNA AFAP1-AS1 supresses miR-139-5p and promotes cell proliferation and chemotherapy resistance of non-small cell lung cancer by competitively …

N Huang, W Guo, K Ren, W Li, Y Jiang, J Sun… - Frontiers in …, 2019 - frontiersin.org
Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related death
worldwide. This study aims to understand the underlying mechanism of lncRNA, actin …

Crosstalk between long non-coding RNAs and p53 signaling pathway in colorectal cancer: A review study

MM Khanifar, Z Zafari, M Sheykhhasan - Pathology-Research and Practice, 2023 - Elsevier
Colorectal cancer (CRC) is one of the most prevalent malignancies worldwide and the third
leading cause of cancer-related fatalities. Long non-coding RNAs (lncRNAs) are key …

LncRNA MEG3 inhibits cell epithelial-mesenchymal transition by sponging miR-421 targeting E-cadherin in breast cancer

W Zhang, S Shi, J Jiang, X Li, H Lu, F Ren - Biomedicine & …, 2017 - Elsevier
Background MEG3, a lncRNA, has been verified in several tumors to function as tumor
suppressors including breast cancer development and progression, however, the …

[HTML][HTML] Dysfunction of the WT1-MEG3 signaling promotes AML leukemogenesis via p53-dependent and-independent pathways

Y Lyu, J Lou, Y Yang, J Feng, Y Hao, S Huang, L Yin… - Leukemia, 2017 - nature.com
Long non-coding RNAs (lncRNAs) play a pivotal role in tumorigenesis, exemplified by the
recent finding that lncRNA maternally expressed gene 3 (MEG3) inhibits tumor growth in a …