Upregulation of the long noncoding RNA PCAT-1 correlates with advanced clinical stage and poor prognosis in esophageal squamous carcinoma

W Shi, Q Wu, S Li, T Yang, Z Liu, Y Tong, L Tuo… - Tumor Biology, 2015 - Springer
Recent studies reveal that long noncoding RNAs (lncRNAs) play critical regulatory roles in
cancer biology. Prostate cancer-associated ncRNA transcript 1 (PCAT-1) is one of the …

Downregulated long non-coding RNA MEG3 in breast cancer regulates proliferation, migration and invasion by depending on p53's transcriptional activity

L Sun, Y Li, B Yang - Biochemical and biophysical research …, 2016 - Elsevier
Long non-coding RNAs (lncRNAs) was found to play critical roles in tumorigenesis, hence,
screen of tumor-related lncRNAs, identification of their biological roles is important for …

Long non‐coding RNA: a new paradigm for lung cancer

A Khandelwal, A Bacolla, KM Vasquez… - Molecular …, 2015 - Wiley Online Library
Lung cancer is the leading cause of cancer‐related deaths worldwide. Recent advances in
whole genome transcriptome analysis have enabled the identification of numerous …

LncRNA-MEG3 inhibits cell proliferation of endometrial carcinoma by repressing Notch signaling

Q Guo, Z Qian, D Yan, LI Li, L Huang - Biomedicine & pharmacotherapy, 2016 - Elsevier
Background The long non-coding RNA MEG3 has shown functional role as a tumor
suppressor in many cancer types, excluding endometrial carcinoma (EC). Thus, this study …

[HTML][HTML] Armored long non-coding RNA MEG3 targeting EGFR based on recombinant MS2 bacteriophage virus-like particles against hepatocellular carcinoma

L Chang, G Wang, T Jia, L Zhang, Y Li, Y Han… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is one of the most frequently diagnosed cancers
worldwide. However, the treatment of patients with HCC is particularly challenging. Long …

[PDF][PDF] Overexpression of HIF-2alpha-dependent NEAT1 promotes the progression of non-small cell lung cancer through miR-101-3p/SOX9/Wnt/beta-catenin signal …

X Kong, Y Zhao, X Li, Z Tao, M Hou… - Cell Physiol …, 2019 - pdfs.semanticscholar.org
Abstract Background/Aims: The present study aimed to explore the function of NEAT1 on
non-small cell lung cancer (NSCLC), as well as its underlying mechanisms. Methods …

[HTML][HTML] New insights into long non-coding RNAs in non-small cell lung cancer

R Ye, R Tang, S Gan, R Li, Y Cheng, L Guo… - Biomedicine & …, 2020 - Elsevier
Lung cancer is a malignant tumor that seriously threatens human life and health. Non-small
cell lung cancer (NSCLC) accounts for 85% of all lung cancer cases, and its global 5-year …

Role of lncRNAs in aging and age‐related diseases

J He, C Tu, Y Liu - Aging Medicine, 2018 - Wiley Online Library
Aging is progressive physiological degeneration and consequently declined function, which
is linked to senescence on both cellular and organ levels. Accumulating studies indicate that …

LncRNA MEG3 inhibit endometrial carcinoma tumorigenesis and progression through PI3K pathway

KX Sun, DD Wu, S Chen, Y Zhao, ZH Zong - Apoptosis, 2017 - Springer
Long noncoding RNAs (lncRNAs) are RNA molecules more than 200 nucleotides in length
that do not encode proteins. Recent studies have reported increasing numbers of functional …

LncRNA MEG3 impacts proliferation, invasion, and migration of ovarian cancer cells through regulating PTEN

J Wang, W Xu, Y He, Q Xia, S Liu - Inflammation Research, 2018 - Springer
Objective and design We investigated the expressions of lncRNA MEG3 and PTEN in
ovarian cancer tissues and their effects on cell proliferation, cycle and apoptosis of ovarian …