[HTML][HTML] Long non-coding RNA LINC01133 represses KLF2, P21 and E-cadherin transcription through binding with EZH2, LSD1 in non small cell lung cancer

C Zang, F Nie, Q Wang, M Sun, W Li, J He, M Zhang… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Long non-coding RNAs are emerging as crucial regulators and prognostic markers in
multiple cancers including non small cell lung cancer (NSCLC). In this study, we screened …

[HTML][HTML] Knockdown of long non-coding RNA TP73-AS1 inhibits cell proliferation and induces apoptosis in esophageal squamous cell carcinoma

W Zang, T Wang, Y Wang, X Chen, Y Du, Q Sun, M Li… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Recent studies have shown that long non-coding RNAs (lncRNAs) are involved in a variety
of biological processes and diseases in humans, including cancer. Our study serves as the …

Long noncoding RNAs as diagnostic and therapeutic targets in type 2 diabetes and related complications

F Leti, JK DiStefano - Genes, 2017 - mdpi.com
Protein-coding genes represent only a small fraction of the human genome. In the past, the
majority of the genomic sequence has been considered transcriptionally silent, but recent …

[HTML][HTML] HBx-related long non-coding RNA DBH-AS1 promotes cell proliferation and survival by activating MAPK signaling in hepatocellular carcinoma

J Huang, T Ren, S Cao, S Zheng, X Hu, Y Hu, L Lin… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Accumulating evidence supports an important role for the hepatitis B virus x protein (HBx) in
the pathogenesis of hepatitis B virus (HBV)-induced hepatocellular carcinoma (HCC), but …

[HTML][HTML] Emerging roles of p53 related lncRNAs in cancer progression: a systematic review

T Lin, PF Hou, S Meng, F Chen, T Jiang… - … journal of biological …, 2019 - ncbi.nlm.nih.gov
Abstract p53 is the major mediator of the tumor suppressor response. It participates in
apoptosis and senescence and can respond to DNA damage. As a crucial sequence …

LncRNA NR2F2‐AS1 promotes tumourigenesis through modulating BMI1 expression by targeting miR‐320b in non‐small cell lung cancer

S Zhang, X Zhang, Q Sun, C Zhuang… - Journal of Cellular …, 2019 - Wiley Online Library
Recently, long noncoding RNAs (lncRNAs) are attracting wide attention in the field of cancer
research because of its important role in cancer diagnosis and prognosis. But studies on the …

Fenofibrate inhibited pancreatic cancer cells proliferation via activation of p53 mediated by upregulation of LncRNA MEG3

D Hu, C Su, M Jiang, Y Shen, A Shi, F Zhao… - Biochemical and …, 2016 - Elsevier
There is still no suitable drug for pancreatic cancer treatment, which is one of the most
aggressive human tumors. Maternally expressed gene 3 (MEG3), a LncRNA, has been …

MEG3 activated by vitamin D inhibits colorectal cancer cells proliferation and migration via regulating clusterin

Y Zhu, P Chen, Y Gao, N Ta, Y Zhang, J Cai, Y Zhao… - …, 2018 - thelancet.com
The long non-coding RNA maternally expressed gene 3 (MEG3) is frequently dysregulated
in human cancers; however, its roles in colorectal cancer (CRC) development are largely …

Long noncoding RNA LINP1 acts as an oncogene and promotes chemoresistance in breast cancer

Y Liang, Y Li, X Song, N Zhang, Y Sang… - Cancer biology & …, 2018 - Taylor & Francis
Recent studies have shown that long non-coding RNAs (lncRNAs) are involved in a number
of biological processes; however, further study is still warranted to comprehensively reveal …

RNA-binding proteins in acute leukemias

K Schuschel, M Helwig, S Hüttelmaier, D Heckl… - International journal of …, 2020 - mdpi.com
Acute leukemias are genetic diseases caused by translocations or mutations, which
dysregulate hematopoiesis towards malignant transformation. However, the molecular mode …