Prevalence and health outcomes of polypharmacy and hyperpolypharmacy in older adults with frailty: a systematic review and meta-analysis

JJY Toh, H Zhang, YY Soh, Z Zhang, XV Wu - Ageing research reviews, 2023 - Elsevier
Polypharmacy is a prevalent issue in older adults, associated with a wide range of adverse
health outcomes, amplified in those with frailty. This review aims to synthesize current …

Facing the challenge of polypharmacy when prescribing for older people with cardiovascular disease. A review by the European Society of Cardiology Working Group …

J Tamargo, KP Kjeldsen, E Delpón… - European Heart …, 2022 - academic.oup.com
Population ageing has resulted in an increasing number of older people living with chronic
diseases (multimorbidity) requiring five or more medications daily (polypharmacy). Ageing …

Risk factors for self-reported medication adherence in community-dwelling older patients with multimorbidity and polypharmacy: a multicenter cross-sectional study

J Liu, Y Yu, S Yan, Y Zeng, S Su, T He, Z Wang, Q Ding… - BMC geriatrics, 2023 - Springer
Background Medication nonadherence is a significant public health problem as it
contributes to poor clinical outcomes and increased healthcare costs. Older patients with …

Potentially inappropriate medication and attitudes of older adults towards deprescribing

AB Achterhof, Z Rozsnyai, E Reeve, KT Jungo… - PloS one, 2020 - journals.plos.org
Introduction Multimorbidity and polypharmacy are current challenges when caring for the
older population. Both have led to an increase of potentially inappropriate medication (PIM) …

Interventions to improve medicines optimisation in frail older patients in secondary and acute care settings: a systematic review of randomised controlled trials and non …

D Saeed, G Carter, C Parsons - International journal of clinical pharmacy, 2022 - Springer
Background: Frailty is a geriatric syndrome in which physiological systems have decreased
reserve and resistance against stressors. Frailty is associated with polypharmacy …

[HTML][HTML] Utilization and spending on potentially inappropriate medications by US older adults with multiple chronic conditions using multiple medications

KT Jungo, S Streit, JC Lauffenburger - Archives of gerontology and …, 2021 - Elsevier
Background The utilization of potentially inappropriate medications (PIMs) in older adults
can lead to adverse events and increased healthcare costs. Polypharmacy, the concurrent …

Frequency and acceptance of clinical decision support system-generated STOPP/START signals for hospitalised older patients with polypharmacy and multimorbidity

BTGM Sallevelt, CJA Huibers, JMJO Heij, TCG Egberts… - Drugs & aging, 2022 - Springer
Abstract Background The Screening Tool of Older Persons' Prescriptions
(STOPP)/Screening Tool to Alert to Right Treatment (START) instrument is used to evaluate …

Team approach to polypharmacy evaluation and reduction: study protocol for a randomized controlled trial

D Mangin, L Lamarche, G Agarwal, HL Banh… - Trials, 2021 - Springer
Background Polypharmacy in older adults can be associated with negative outcomes
including falls, impaired cognition, reduced quality of life, and general and functional …

Appropriateness of medications in older adults living with frailty: impact of a pharmacist-led structured medication review process in primary care

S Khera, M Abbasi, J Dabravolskaj… - Journal of Primary …, 2019 - journals.sagepub.com
Background: Older persons with frailty take multiple medications and are vulnerable to
inappropriate prescribing. Objective: This study assesses the impact of a team-based …

International validation of the Turkish Inappropriate Medication Use in the Elderly (TIME) criteria set: a Delphi panel study

G Bahat, B Ilhan, T Erdogan, MM Oren, MA Karan… - Drugs & aging, 2021 - Springer
Objective Explicit screening tools and implicit evaluation methods have been developed to
assist healthcare professionals in the management of pharmacotherapy in older adults. As …