Spinal cord injury: molecular mechanisms and therapeutic interventions
X Hu, W Xu, Y Ren, Z Wang, X He, R Huang… - Signal transduction and …, 2023 - nature.com
Spinal cord injury (SCI) remains a severe condition with an extremely high disability rate.
The challenges of SCI repair include its complex pathological mechanisms and the …
The challenges of SCI repair include its complex pathological mechanisms and the …
Progress in stem cell therapy for spinal cord injury
L Gao, Y Peng, W Xu, P He, T Li, X Lu… - Stem Cells …, 2020 - Wiley Online Library
Background. Spinal cord injury (SCI) is one of the serious neurological diseases that occur
in young people with high morbidity and disability. However, there is still a lack of effective …
in young people with high morbidity and disability. However, there is still a lack of effective …
Minimally invasive and regenerative therapeutics
Advances in biomaterial synthesis and fabrication, stem cell biology, bioimaging,
microsurgery procedures, and microscale technologies have made minimally invasive …
microsurgery procedures, and microscale technologies have made minimally invasive …
Molecular mechanisms and clinical application of multipotent stem cells for spinal cord injury
M Szymoniuk, J Litak, L Sakwa, A Dryla, W Zezuliński… - Cells, 2022 - mdpi.com
Spinal Cord Injury (SCI) is a common neurological disorder with devastating psychical and
psychosocial sequelae. The majority of patients after SCI suffer from permanent disability …
psychosocial sequelae. The majority of patients after SCI suffer from permanent disability …
Clinical trials of stem cell treatment for spinal cord injury
K Yamazaki, M Kawabori, T Seki, K Houkin - International Journal of …, 2020 - mdpi.com
There are more than one million patients worldwide suffering paralysis caused by spinal
cord injury (SCI). SCI causes severe socioeconomic problems not only to the patients and …
cord injury (SCI). SCI causes severe socioeconomic problems not only to the patients and …
Stem cells therapy for spinal cord injury: an overview of clinical trials
S Silvestro, P Bramanti, O Trubiani… - International Journal of …, 2020 - mdpi.com
Spinal cord injury (SCI) is a traumatic lesion that causes disability with temporary or
permanent sensory and/or motor deficits. The pharmacological approach still in use for the …
permanent sensory and/or motor deficits. The pharmacological approach still in use for the …
Exosomes and exosome-loaded scaffolds: characterization and application in modern regenerative medicine
Exosomes (EXOs) are extracellular vesicles derived from the endosome. These
heterogeneous nanoparticles (30–150 nm) are secreted from various cells and play …
heterogeneous nanoparticles (30–150 nm) are secreted from various cells and play …
CELLTOP clinical trial: first report from a phase 1 trial of autologous adipose tissue–derived mesenchymal stem cells in the treatment of paralysis due to traumatic …
Spinal cord injury (SCI) is a devastating condition with limited pharmacological treatment
options to restore function. Regenerative approaches have recently attracted interest as an …
options to restore function. Regenerative approaches have recently attracted interest as an …
Mesenchymal stem cells as a multimodal treatment for nervous system diseases
B Badyra, M Sułkowski, O Milczarek… - Stem Cells …, 2020 - academic.oup.com
Neurological disorders are a massive challenge for modern medicine. Apart from the fact
that this group of diseases is the second leading cause of death worldwide, the majority of …
that this group of diseases is the second leading cause of death worldwide, the majority of …
Effects of mesenchymal stem cell transplantation on spinal cord injury patients
F Tahmasebi, S Barati - Cell and Tissue Research, 2022 - Springer
Spinal cord injury (SCI) is a traumatic injury with sensory and motor deficits that more than 1
million patients worldwide suffer from disability due to it. Many pharmacological therapies …
million patients worldwide suffer from disability due to it. Many pharmacological therapies …