Further understanding the connection between Alzheimer's disease and Down syndrome

HM Snyder, LJ Bain, AM Brickman… - Alzheimer's & …, 2020 - Wiley Online Library
Improved medical care of individuals with Down syndrome (DS) has led to an increase in life
expectancy to over the age of 60 years. In conjunction, there has been an increase in age …

Sleep disorders in adults with Down syndrome

S Giménez, M Altuna, E Blessing, RM Osorio… - Journal of clinical …, 2021 - mdpi.com
Sleep disorders, despite being very frequent in adults with Down syndrome (DS), are often
overlooked due to a lack of awareness by families and physicians and the absence of …

Multiple morbidity across the lifespan in people with Down syndrome or intellectual disabilities: a population-based cohort study using electronic health records

RA Baksh, SE Pape, LF Chan, AA Aslam… - The Lancet Public …, 2023 - thelancet.com
Summary Background The Down syndrome phenotype is well established, but our
understanding of its morbidity patterns is limited. We comprehensively estimated the risk of …

British Thoracic Society Guideline for diagnosing and monitoring paediatric sleep-disordered breathing

HJ Evans, NA Gibson, J Bennett, SYS Chan, J Gavlak… - Thorax, 2023 - thorax.bmj.com
Recommendations► The Sleep-Related Breathing Disorder scale of the Paediatric Sleep
Questionnaire (SRBD-PSQ), with a cut-off of≥ 0.33, or Obstructive Sleep Apnoea-18 item …

Obstructive sleep apnoea contributes to executive function impairment in young children with Down syndrome

A Joyce, H Elphick, M Farquhar, P Gringras… - Behavioral sleep …, 2020 - Taylor & Francis
ABSTRACT Objective/Background Children with Down syndrome (DS) commonly
experience difficulties with executive function (EF). They are also vulnerable to obstructive …

Overweight/obesity and chronic health conditions in older people with intellectual disability in Ireland

J Ryan, P McCallion, M McCarron… - Journal of …, 2021 - Wiley Online Library
Background This study examines overweight/obesity and chronic health conditions (CHCs)
in older people with intellectual disability (ID). Methods Data for this cross‐sectional …

Sleep apnea in children with down syndrome

K Seither, BM Helm, C Heubi, D Swarr, KR Suhrie - Pediatrics, 2023 - publications.aap.org
OBJECTIVE The authors of this study aimed to evaluate the use of polysomnography (PSG)
in children with Down syndrome (DS) between ages 0 and 7 years, to assess the prevalence …

Treatment considerations for obstructive sleep apnea in pediatric Down syndrome

E Gastelum, M Cummins, A Singh, M Montoya… - Children, 2021 - mdpi.com
Children with Down syndrome (DS) are at high risk for developing obstructive sleep apnea
(OSA) compared to children without DS. The negative impact of OSA on health, behavior …

Obstructive sleep apnea syndrome in adults with down syndrome: Causes and consequences. Is it a" chicken and egg" question?

L Dumortier, VA Bricout - Neuroscience & Biobehavioral Reviews, 2020 - Elsevier
Individuals with Down syndrome present many clinical characteristics, such as metabolic,
endocrine, anatomic and neurologic dysfunctions, that contribute to the physiopathology of …

Advances in the use of hypoglossal nerve stimulator in adolescents with down syndrome and persistent obstructive sleep apnea—a systematic review

F Rodriguez Lara, JM Carnino… - Annals of Otology …, 2024 - journals.sagepub.com
Introduction: The Hypoglossal Nerve Stimulator (HNS) is a novel therapy that has been
extensively studied in adults and more recently, it has been incorporated in children with …