The bioavailability, transport, and bioactivity of dietary flavonoids: A review from a historical perspective
Flavonoids are plant‐derived dietary components with a substantial impact on human
health. Research has expanded massively since it began in the 1930s, and the complex …
health. Research has expanded massively since it began in the 1930s, and the complex …
[HTML][HTML] Silymarin as a natural antioxidant: an overview of the current evidence and perspectives
PF Surai - Antioxidants, 2015 - mdpi.com
Silymarin (SM), an extract from the Silybum marianum (milk thistle) plant containing various
flavonolignans (with silybin being the major one), has received a tremendous amount of …
flavonolignans (with silybin being the major one), has received a tremendous amount of …
[HTML][HTML] Diet-derived antioxidants: the special case of ergothioneine
B Halliwell, RMY Tang, IK Cheah - Annual Review of Food …, 2023 - annualreviews.org
This article reviews what is presently known about the biological roles of the diet-derived
compound ergothioneine (ET). ET seems important to humans because it is rapidly taken up …
compound ergothioneine (ET). ET seems important to humans because it is rapidly taken up …
Plant phenolics as functional food ingredients
C Santos-Buelga, AM González-Paramás… - Advances in food and …, 2019 - Elsevier
Phenolic compounds have attracted much attention in recent times as their dietary intake
has been associated with the prevention of some chronic and degenerative diseases that …
has been associated with the prevention of some chronic and degenerative diseases that …
[HTML][HTML] Identifying the limits for ellagic acid bioavailability: A crossover pharmacokinetic study in healthy volunteers after consumption of pomegranate extracts
A González-Sarrías, R García-Villalba… - Journal of Functional …, 2015 - Elsevier
Ellagic acid (EA) is a polyphenol that must be released from the non-bioavailable
ellagitannins in pomegranates, walnuts or strawberries to be absorbed. To estimate whether …
ellagitannins in pomegranates, walnuts or strawberries to be absorbed. To estimate whether …
Phenolic compounds that cross the blood–brain barrier exert positive health effects as central nervous system antioxidants
D Velásquez-Jiménez, DA Corella-Salazar… - Food & Function, 2021 - pubs.rsc.org
The blood–brain barrier (BBB) is a physical structure whose main function is to strictly
regulate access to circulating compounds into the central nervous system (CNS). Vegetable …
regulate access to circulating compounds into the central nervous system (CNS). Vegetable …
Polyphenolic phytochemicals in cancer prevention and therapy: bioavailability versus bioefficacy
JM Estrela, S Mena, E Obrador… - Journal of medicinal …, 2017 - ACS Publications
Natural polyphenols are organic chemicals which contain phenol units in their structures.
They show antitumor properties. However, a key problem is their short half-life and low …
They show antitumor properties. However, a key problem is their short half-life and low …
[HTML][HTML] Considerations for the use of polyphenols as therapies in neurodegenerative diseases
J Renaud, MG Martinoli - International Journal of Molecular Sciences, 2019 - mdpi.com
Over the last two decades, the increase in the incidence of neurodegenerative diseases due
to the increasingly ageing population has resulted in a major social and economic burden …
to the increasingly ageing population has resulted in a major social and economic burden …
Structural diversity of polyphenols and distribution in foods
A González‐Sarrías… - … and health effects, 2020 - Wiley Online Library
Summary (Poly) Phenolic compounds or polyphenols are the most common and ubiquitous
groups of secondary metabolites widely distributed in the plant kingdom. These metabolites …
groups of secondary metabolites widely distributed in the plant kingdom. These metabolites …
[HTML][HTML] Antioxidants in potatoes: A functional view on one of the major food crops worldwide
With a growing world population, accelerating climate changes, and limited arable land, it is
critical to focus on plant-based resources for sustainable food production. In addition, plants …
critical to focus on plant-based resources for sustainable food production. In addition, plants …