Despite the success of antiretroviral therapy (ART) for people living with HIV, lifelong
treatment is required and there is no cure. HIV can integrate in the host genome and persist …

The development of antiretroviral therapy for the prevention and treatment of HIV infection
has been marked by a series of remarkable successes. However, the efforts to develop a …

Despite scientific evidence originating from two patients published to date that
CCR5Δ32/Δ32 hematopoietic stem cell transplantation (HSCT) can cure human …

Sustained, drug-free control of HIV-1 replication is naturally achieved in less than 0.5% of
infected individuals (here termed 'elite controllers'), despite the presence of a replication …

A cure for HIV-1 remains unattainable as only one case has been reported, a decade ago,.
The individual—who is known as the 'Berlin patient'—underwent two allogeneic …

In the quest for a functional cure or the eradication of HIV infection, it is necessary to know
the sizes of the reservoirs from which infection rebounds after treatment interruption. Thus …

Summary Background The London patient (participant 36 in the IciStem cohort) underwent
allogeneic stem-cell transplantation with cells that did not express CCR5 (CCR5Δ32/Δ32); …

The success of antiretroviral therapy has led some people to now ask whether the end of
AIDS is possible. For patients who are motivated to take therapy and who have access to …

Antiretroviral therapy is not curative. Given the challenges in providing lifelong therapy to a
global population of more than 35 million people living with HIV, there is intense interest in …

HIV prevalence is increasing worldwide because people on antiretroviral therapy are living
longer, although new infections decreased from 3· 3 million in 2002, to 2· 3 million in 2012 …