Understanding the rise of the superbug: investigation of the evolution and genomic variation of Staphylococcus aureus

JA Lindsay, MTG Holden - Functional & integrative genomics, 2006 - Springer
The bacterium Staphylococcus aureus is a common cause of human infection, and it is
becoming increasingly virulent and resistant to antibiotics. Our understanding of the …

[HTML][HTML] Enzymatic modifications of exopolysaccharides enhance bacterial persistence

GB Whitfield, LS Marmont, PL Howell - Frontiers in microbiology, 2015 - frontiersin.org
Biofilms are surface-attached communities of bacterial cells embedded in a self-produced
matrix that are found ubiquitously in nature. The biofilm matrix is composed of various …

Características generales del Staphylococcus aureus

E Cervantes-García, R García-González… - Revista Mexicana de …, 2014 - medigraphic.com
Desde su descubrimiento por el médico Alexander Ogston en 1880, Staphylococcus aureus
es considerado un patógeno con gran potencial para causar múltiples infecciones en el …

Memory Th1 Cells Are Protective in Invasive Staphylococcus aureus Infection

AF Brown, AG Murphy, SJ Lalor, JM Leech… - PLoS …, 2015 - journals.plos.org
Mechanisms of protective immunity to Staphylococcus aureus infection in humans remain
elusive. While the importance of cellular immunity has been shown in mice, T cell responses …

Rare Occurrence of Methicillin-Resistant Staphylococcus aureus CC130 with a Novel mecA Homologue in Humans in Germany

C Cuny, F Layer, B Strommenger, W Witte - PloS one, 2011 - journals.plos.org
MRSA CC130 containing the mec A homologue mec ALGA251 were reported from the UK
and from Denmark so far from cattle and humans. Here we report on 11 MRSA CC130 …

Evolutionarily distinct bacteriophage endolysins featuring conserved peptidoglycan cleavage sites protect mice from MRSA infection

M Schmelcher, Y Shen, DC Nelson… - Journal of …, 2015 - academic.oup.com
Objectives In the light of increasing drug resistance in Staphylococcus aureus,
bacteriophage endolysins [peptidoglycan hydrolases (PGHs)] have been suggested as …

Identification of Staphylococcus aureus Proteins Recognized by the Antibody-Mediated Immune Response to a Biofilm Infection

RA Brady, JG Leid, AK Camper… - Infection and …, 2006 - Am Soc Microbiol
Staphylococcus aureus causes persistent, recurrent infections (eg, osteomyelitis) by forming
biofilms. To survey the antibody-mediated immune response and identify those proteins that …

Bacteria and Host Interplay in Staphylococcus aureus Septic Arthritis and Sepsis

T Jin, M Mohammad, R Pullerits, A Ali - Pathogens, 2021 - mdpi.com
Staphylococcus aureus (S. aureus) infections are a major healthcare challenge and new
treatment alternatives are needed. S. aureus septic arthritis, a debilitating joint disease …

Efficacy profile of a bivalent Staphylococcus aureus glycoconjugated vaccine in adults on hemodialysis: Phase III randomized study

A Fattom, A Matalon, J Buerkert, K Taylor… - Human vaccines & …, 2015 - Taylor & Francis
In a previous study in end-stage renal disease (ESRD) hemodialysis patients, a single dose
of Staphylococcus aureus type 5 and 8 capsular polysaccharides (T5/T8) conjugated to …

Staphylococcus aureus CcpA Affects Virulence Determinant Production and Antibiotic Resistance

K Seidl, M Stucki, M Ruegg, C Goerke… - Antimicrobial agents …, 2006 - Am Soc Microbiol
Carbon catabolite protein A (CcpA) is known to function as a major regulator of gene
expression in different gram-positive organisms. Deletion of the ccpA homologue …