Surveillance of fluoroquinolones resistance in rifampicin-susceptible tuberculosis in eastern China with whole-genome sequencing-based approach
Y Che, Y Lu, Y Zhu, T He, X Li, J Gao, J Gao… - Frontiers in …, 2024 - frontiersin.org
Background Leveraging well-established DNA-level drug resistance mechanisms, whole-
genome sequencing (WGS) has emerged as a valuable methodology for predicting drug …
genome sequencing (WGS) has emerged as a valuable methodology for predicting drug …
Evaluation of whole-genome sequence to predict drug resistance of nine anti-tuberculosis drugs and characterize resistance genes in clinical rifampicin-resistant …
Y Che, Y Lin, T Yang, T Chen, G Sang… - Frontiers in Public …, 2022 - frontiersin.org
Setting Controlling drug-resistant tuberculosis in Ningbo, China. Objective Whole-genome
sequencing (WGS) has not been employed to comprehensively study Mycobacterium …
sequencing (WGS) has not been employed to comprehensively study Mycobacterium …
Role of the first WHO mutation catalogue in the diagnosis of antibiotic resistance in Mycobacterium tuberculosis in the Valencia Region, Spain: a retrospective …
AM García-Marín, I Cancino-Muñoz… - The Lancet …, 2024 - thelancet.com
Summary Background In June, 2021, WHO published the most complete catalogue to date
of resistance-conferring mutations in Mycobacterium tuberculosis. Here, we aimed to assess …
of resistance-conferring mutations in Mycobacterium tuberculosis. Here, we aimed to assess …
Molecular characterization of extended spectrum cephalosporin resistant Escherichia coli isolated from livestock and in-contact humans in Southeast Nigeria
The rise in antimicrobial resistance (AMR) in bacteria is reducing therapeutic options for
livestock and human health, with a paucity of information globally. To fill this gap, a One …
livestock and human health, with a paucity of information globally. To fill this gap, a One …
Whole genome sequencing-based drug resistance predictions of multidrug-resistant Mycobacterium tuberculosis isolates from Tanzania
PM Mbelele, C Utpatel, E Sauli… - JAC-antimicrobial …, 2022 - academic.oup.com
Background Rifampicin-or multidrug-resistant (RR/MDR) Mycobacterium tuberculosis
complex (MTBC) strains account for considerable morbidity and mortality globally. WGS …
complex (MTBC) strains account for considerable morbidity and mortality globally. WGS …
Phenotype versus genotype discordant rifampicin susceptibility testing in tuberculosis: implications for a diagnostic accuracy
ABSTRACT The World Health Organization recommends culture-based techniques as the
gold standard for rifampicin-resistant (RR) tuberculosis. However, as rapid molecular assays …
gold standard for rifampicin-resistant (RR) tuberculosis. However, as rapid molecular assays …
Performance of an Xpert-based diagnostic algorithm for the rapid detection of drug-resistant tuberculosis among high-risk populations in a low-incidence setting
TY Chiang, SY Fan, R Jou - PLoS One, 2018 - journals.plos.org
Timely diagnosis of drug-resistant tuberculosis (DR-TB) is beneficial for case treatment and
management. We implemented an algorithm to improve molecular diagnostic utilization to …
management. We implemented an algorithm to improve molecular diagnostic utilization to …
High throughput sequencing for clinical tuberculosis: an overview
High throughput sequencing (HTS) can identify the presence of Mycobacterium tuberculosis
DNA in a clinical sample while also providing information on drug susceptibility. Multiple …
DNA in a clinical sample while also providing information on drug susceptibility. Multiple …
Genetics and roadblocks of drug resistant tuberculosis
J Perdigao, I Portugal - Infection, Genetics and Evolution, 2019 - Elsevier
Considering the extensive evolutionary history of Mycobacterium tuberculosis, anti-
Tuberculosis (TB) drug therapy exerts a recent selective pressure. However, in a …
Tuberculosis (TB) drug therapy exerts a recent selective pressure. However, in a …
Insight into population structure and drug resistance of pediatric tuberculosis strains from China and Russia gained through whole-genome sequencing
S Zhdanova, WW Jiao, V Sinkov, P Khromova… - International Journal of …, 2023 - mdpi.com
This study aimed to determine phenotypic and genotypic drug resistance patterns of
Mycobacterium tuberculosis strains from children with tuberculosis (TB) in China and …
Mycobacterium tuberculosis strains from children with tuberculosis (TB) in China and …