Bordetella respiratory infections are common in people (B. pertussis) and in animals (B.
bronchiseptica). During the last two decades, much has been learned about the virulence …

The theory proposed is that a critical level of specific serum IgG is sufficient to confer
protection against infectious diseases by inactivating the inoculum of the pathogen. This …

Vaccine efficacies against typical pertussis after household exposure to Bordetella pertussis
were estimated to be 75.4% for an acellular five-component vaccine, 42.4% for an acellular …

Background Although many whole-cell vaccines have been effective in preventing pertussis,
these vaccines are difficult to standardize and can produce side effects. In Sweden …

All acellular pertussis vaccines contain pertussis toxoid and induce protection against
pertussis. This study investigated the relation between the postvaccination levels of …

As immunizations successfully reduce the incidence of their target diseases, the vaccine
community needs to evolve and recognize the increased relative prominence of vaccine …

The recent development of acellular pertussis vaccines has been a significant improvement
in the conventional whole-cell diphtheria-pertussis-tetanus toxoid vaccines, but high …

The selection of acellular vaccine antigens relies on current concepts of pertussis
pathogenesis. Animal model data provide evidence that certain products of Bordetella …

Abstract During 1979–1995, there was no vaccination against pertussis in Sweden. With the
aim of studying the epidemiology and transmission of pertussis, mass vaccination with …

Objective: To examine induction and persistence of cell-mediated immunity (CMI) and
antibody responses toBordetella pertussisantigens in infants receiving antipertussis …