Papillary thyroid microcarcinoma: time to shift from surgery to active surveillance?

S Leboulleux, RM Tuttle, F Pacini… - The lancet Diabetes & …, 2016 - thelancet.com
The incidence of differentiated thyroid cancer is increasing greatly in high-income countries.
Roughly 50% of this increase is attributable to the identification of intrathyroidal papillary …

[HTML][HTML] Radioiodine therapy in advanced differentiated thyroid cancer: Resistance and overcoming strategy

Y Liu, J Wang, X Hu, Z Pan, T Xu, J Xu, L Jiang… - Drug Resistance …, 2023 - Elsevier
Thyroid cancer is the most prevalent endocrine tumor and its incidence is fast-growing
worldwide in recent years. Differentiated thyroid cancer (DTC) is the most common …

Thyroid cancer: risk-stratified management and individualized therapy

F Raue, K Frank-Raue - Clinical Cancer Research, 2016 - AACR
Thyroid cancer is the most common endocrine malignancy. Differentiated thyroid cancer
(DTC) with the two subtypes, papillary thyroid cancer (PTC) and follicular thyroid cancer …

Genetic landscape of papillary thyroid carcinoma and nuclear architecture: an overview comparing pediatric and adult populations

A Rangel-Pozzo, L Sisdelli, MIV Cordioli, F Vaisman… - Cancers, 2020 - mdpi.com
Simple Summary Papillary thyroid carcinoma (PTC) represents 80–90% of all differentiated
thyroid carcinomas. PTC has a high rate of gene fusions and mutations, which can influence …

Fusion oncogenes are the main genetic events found in sporadic papillary thyroid carcinomas from children

MICV Cordioli, L Moraes, AU Bastos, P Besson… - Thyroid, 2017 - liebertpub.com
Background: Previous studies reported significant differences in the clinical presentation
and outcomes of papillary thyroid carcinoma (PTC) in pediatric patients compared with …

Association of BRAFV600E Mutation with the Aggressive Behavior of Papillary Thyroid Microcarcinoma: A Meta-Analysis of 33 Studies

AS Attia, M Hussein, PP Issa, A Elnahla… - International journal of …, 2022 - mdpi.com
An association between the BRAFV600E mutation and the clinicopathological progression
of papillary thyroid microcarcinoma (PTMC) has been suggested. We aimed to summarize …

Cutoff age between pediatric and adult thyroid differentiated cancer: is 18 years old appropriate?

K Sugino, M Nagahama, W Kitagawa, K Ohkuwa… - Thyroid, 2022 - liebertpub.com
Background: The characteristics of pediatric differentiated thyroid cancer (DTC) are
substantially different from those of adult DTC. This study investigated whether the cutoff age …

NIS expression in thyroid tumors, relation with prognosis clinicopathological and molecular features

C Tavares, MJ Coelho, C Eloy, M Melo… - Endocrine …, 2018 - ec.bioscientifica.com
Thyroid cancer therapy is based on surgery followed by radioiodine treatment. The
incorporation of radioiodine by cancer cells is mediated by sodium iodide symporter …

Radio-iodide treatment: from molecular aspects to the clinical view

A De la Vieja, G Riesco-Eizaguirre - Cancers, 2021 - mdpi.com
Simple Summary This year marks the 80th commemoration of the first time that radio-iodide
treatment (RAI) was used. RAI is one of the most effective targeted internal radiation …

[HTML][HTML] Nomogram for predicting central lymph node metastasis in papillary thyroid microcarcinoma: A retrospective cohort study of 8668 patients

Y Wang, Q Guan, J Xiang - International Journal of Surgery, 2018 - Elsevier
Introduction The status of central lymph node metastasis (CLNM) is crucial to determining
the surgical strategies for papillary thyroid micro carcinoma (PTMC). The objective of the …