Hematologic toxicity profile and efficacy of [225Ac]Ac-PSMA-617 α-radioligand therapy of patients with extensive skeletal metastases of castration-resistant prostate …

IO Lawal, A Morgenstern, M Vorster, O Knoesen… - European Journal of …, 2022 - Springer
Abstract Purpose Actinium-225-labeled prostate-specific membrane antigen ([225Ac] Ac-
PSMA-617) is safe and effective in the treatment of metastatic castration-resistant prostate …

[HTML][HTML] Joint EANM/SNMMI procedure guideline for the use of 177Lu-labeled PSMA-targeted radioligand-therapy (177Lu-PSMA-RLT)

C Kratochwil, WP Fendler, M Eiber, MS Hofman… - European journal of …, 2023 - Springer
Prostate-specific membrane antigen (PSMA) is expressed by the majority of clinically
significant prostate adenocarcinomas, and patients with target-positive disease can easily …

177Lu‐PSMA radioligand therapy effectiveness in metastatic castration‐resistant prostate cancer: An updated systematic review and meta‐analysis

MS Sadaghiani, S Sheikhbahaei, RA Werner… - The …, 2022 - Wiley Online Library
Background An updated systematic review and meta‐analysis of relevant studies to
evaluate the effectiveness of prostate‐specific membrane antigen (PSMA)‐targeted …

Actinium-225-PSMA radioligand therapy of metastatic castration-resistant prostate cancer (WARMTH Act): a multicentre, retrospective study

MM Sathekge, IO Lawal, C Bal, F Bruchertseifer… - The Lancet …, 2024 - thelancet.com
Summary Background Actinium-225 (225 Ac) prostate-specific membrane antigen (PSMA)
radioligand therapy (RLT) is a novel therapy for metastatic castration-resistant prostate …

[HTML][HTML] 177Lu-PSMA-617 versus docetaxel in chemotherapy-naïve metastatic castration-resistant prostate cancer: a randomized, controlled, phase 2 non-inferiority …

S Satapathy, BR Mittal, A Sood, CK Das… - European Journal of …, 2022 - Springer
Purpose Lutetium-177 prostate-specific membrane antigen-617 (177 Lu-PSMA-617) in end-
stage metastatic castration-resistant prostate cancer (mCRPC) has reported favourable …

[HTML][HTML] Optimal sequencing and predictive biomarkers in patients with advanced prostate cancer

C Cattrini, R España, A Mennitto, M Bersanelli… - Cancers, 2021 - mdpi.com
Simple Summary Several strategies have demonstrated the ability to improve the survival of
patients with both metastatic and nonmetastatic prostate cancer. The old backbone of …

[HTML][HTML] European Association of Nuclear Medicine Focus 5: consensus on molecular imaging and theranostics in prostate cancer

DE Oprea-Lager, S MacLennan, A Bjartell, A Briganti… - European Urology, 2024 - Elsevier
Abstract Background In prostate cancer (PCa), questions remain on indications for prostate-
specific membrane antigen (PSMA) positron emission tomography (PET) imaging and …

177Lu-PSMA-I&T for treatment of metastatic castration-resistant prostate cancer: prognostic value of scintigraphic and clinical biomarkers

A Karimzadeh, M Heck, R Tauber, K Knorr… - Journal of Nuclear …, 2023 - Soc Nuclear Med
The aim of this retrospective analysis was to determine prostate-specific antigen (PSA)
response, PSA progression-free survival (PFS), and overall survival (OS) in a large cohort of …

[HTML][HTML] Preclinical evaluation of [58mCo]Co-DOTA-PSMA-617 for Auger electron therapy of prostate cancer

C Baun, JH Dam, MG Hildebrandt, JD Ewald… - Scientific Reports, 2023 - nature.com
Prostate-specific membrane antigen (PSMA), highly expressed in prostate cancer, is a
promising target for radionuclide therapy. Auger electron-emitting radionuclides are well …

[HTML][HTML] Update of PSMA theranostics in prostate cancer: current applications and future trends

C Kaewput, S Vinjamuri - Journal of Clinical Medicine, 2022 - mdpi.com
There is now an increasing trend for targeting cancers to go beyond early diagnosis and
actually improve Progression-Free Survival and Overall Survival. Identifying patients who …