[HTML][HTML] Brugada syndrome in Thailand: Three decades of progress

G Veerakul, A Khongphatthanayothin, K Nademanee - Heart Rhythm O2, 2022 - Elsevier
Our group began investigating the cause of sudden unexplained death syndrome in
Thailand in 1994 and found that among sudden unexplained death syndrome patients, the …

Clinical characteristics and electrophysiologic properties of SCN5A variants in fever-induced Brugada syndrome

GX Chen, H Barajas-Martínez, G Ciconte, CI Wu… - …, 2023 - thelancet.com
Summary Background Brugada syndrome (BrS) is a severe inherited arrhythmia syndrome
that can be unmasked by fever. Methods A multicentre clinical analysis was performed in …

[HTML][HTML] J-Wave Syndromes, SCN5A, and Cardiac Conduction Reserve: Two Sides of the Same Coin?

ER Behr - Journal of the American College of Cardiology, 2021 - jacc.org
The Brugada syndrome (BrS) and early repolarization syndrome (ERS) both associate
typical electrocardiography (ECG) traits with the risk for cardiac arrest and sudden death …

Novel SCN5A Variant Shows Multiple Phenotypic Expression in the Same Family

C Balla, D Mele, F Vitali, C Andreoli… - Circulation: Genomic …, 2021 - Am Heart Assoc
Brugada pattern during routine ECG before elective surgery. The ECG was recorded at
standard and highlead position (Figure, 1A). He reported previous episodes of syncope with …

[HTML][HTML] Antiarrhythmic effect of artemisinin in an ex-vivo model of Brugada syndrome induced by NS5806

HK Jeong, SN Hong, N Yoon, KH Lee… - Korean Circulation …, 2023 - synapse.koreamed.org
Methods Transmural pseudo-electrocardiograms and epicardial/endocardial
transmembrane action potentials (APs) were recorded from coronary-perfused canine right …

Identification of a novel missense SCN5A mutation in a Chinese Han family with Brugada syndrome

J Zhu, Y Shen, H Xiong, H Zha, L Zhang, H Peng… - Biochemical and …, 2023 - Elsevier
Brugada syndrome is an inherited cardiac arrythmia causes sudden death usually
associated with loss-of-function mutations of SCN5A, a gene encodes α subunit of cardiac …

Delayed depolarization and histologic abnormalities underlie the Brugada syndrome

B Martini, N Martini, L De Mattia… - Pacing and Clinical …, 2023 - Wiley Online Library
Brugada syndrome (BrS) is a controversial disease whose pathophysiology is still far from
being fully understood. Unlike other cardiological disorders, a definite etiology has not yet …

Counterpoint: Ablation in long QT syndrome

AAM Wilde, MJ Ackerman - Heart rhythm, 2023 - heartrhythmjournal.com
Long QT syndrome (LQTS) is the most common and most well established genetic
arrhythmia syndrome/primary electrical disease, caused by pathogenic disease–causative …

Mutations in MYBPC3 and MYH7 in Association with Brugada Type 1 ECG Pattern: Overlap between Brugada Syndrome and Hypertrophic Cardiomyopathy?

M Farnè, C Balla, A Margutti, R Selvatici, M De Raffele… - Cardiogenetics, 2021 - mdpi.com
Brugada syndrome (BrS) is an inherited disorder with high allelic and genetic heterogeneity
clinically characterized by typical coved-type ST segment elevation at the electrocardiogram …

The role of electrophysiological study in the risk stratification of Brugada syndrome

G Bazoukis, CT Chung, VS Vassiliou… - Cardiology in …, 2023 - journals.lww.com
Brugada syndrome (BrS) is a complex arrhythmogenic disease associated with an
increased risk of sudden cardiac death (SCD). The role of electrophysiological study (EPS) …