Neurobiological mechanisms of nicotine reward and aversion

L Wills, JL Ables, KM Braunscheidel, SPB Caligiuri… - Pharmacological …, 2022 - ASPET
Neuronal nicotinic acetylcholine receptors (nAChRs) regulate the rewarding actions of
nicotine contained in tobacco that establish and maintain the smoking habit. nAChRs also …

Diversity of native nicotinic receptor subtypes in mammalian brain

M Zoli, F Pistillo, C Gotti - Neuropharmacology, 2015 - Elsevier
Neuronal nicotinic acetylcholine receptors (nAChRs) are a heterogeneous family of
pentameric ligand-gated cation channels that are expressed throughout the brain and …

Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calcium

P Séguéla, J Wadiche, K Dineley-Miller… - Journal of …, 1993 - Soc Neuroscience
A full-length clone coding for the rat alpha 7 nicotinic receptor subunit was isolated from an
adult brain cDNA library and expressed in Xenopus oocytes. A significant proportion of the …

Neurotransmitter actions in the thalamus and cerebral cortex and their role in neuromodulation of thalamocortical activity

DA McCormick - Progress in neurobiology, 1992 - Elsevier
3.3. Electrophysiological basis of tonic firing in thalamic relay neurons 3.4. High frequency
(30-50 Hz) rhythms in thalamic neurons 3.5. Functional consequences of …

Neuronal nicotinic receptors in the human brain

D Paterson, A Nordberg - Progress in neurobiology, 2000 - Elsevier
Neuronal nicotinic acetylcholine receptors (nAChRs) are a family of ligand gated ion
channels which are widely distributed in the human brain. Multiple subtypes of these …

Cognitive functions of cortical acetylcholine: toward a unifying hypothesis

M Sarter, JP Bruno - Brain Research Reviews, 1997 - Elsevier
Previous efforts aimed at attributing discrete behavioral functions to cortical cholinergic
afferents have not resulted in a generally accepted hypothesis about the behavioral …

Distribution of alpha2, alpha3, alpha4, and beta2 neuronal nicotinic receptor subunit mRNAs in the central nervous system: a hybridization histochemical study in the …

E Wada, K Wada, JIM Boulter, E Deneris… - Journal of …, 1989 - Wiley Online Library
Previous studies have revealed the existence of a gene family that encodes a group of
neuronal nicotinic acetylcholine receptor (nAChR) subunits. Four members of this family …

Neuromodulatory transmitter systems in the cortex and their role in cortical plasticity

Q Gu - Neuroscience, 2002 - Elsevier
Cortical neuromodulatory transmitter systems refer to those classical neurotransmitters such
as acetylcholine and monoamines, which share a number of common features. For instance …

Mechanisms in the bed nucleus of the stria terminalis involved in control of autonomic and neuroendocrine functions: a review

CC Crestani, FHF Alves, FV Gomes… - Current …, 2013 - ingentaconnect.com
The bed nucleus of the stria terminalis (BNST) is a heterogeneous and complex limbic
forebrain structure, which plays an important role in controlling autonomic, neuroendocrine …

Physiological diversity of nicotinic acetylcholine receptors expressed by vertebrate neurons.

DS McGehee, LW Role - Annual review of physiology, 1995 - psycnet.apa.org
Reviews the literature on how the behavioral, cognitive, and addictive effects of nicotine can
be reconciled with the paucity of evidence for CNS synapses where the transmission is …