Movement disorder and sensorimotor abnormalities in schizophrenia and other psychoses-European consensus on assessment and perspectives

S Walther, PN van Harten, JL Waddington… - European …, 2020 - Elsevier
Over the last three decades, movement disorder as well as sensorimotor and psychomotor
functioning in schizophrenia (SZ) and other psychoses has gained greater scientific and …

A systematic review of the prognostic value of motor abnormalities on clinical outcome in psychosis

LE Pieters, N Nadesalingam, S Walther… - Neuroscience & …, 2022 - Elsevier
Schizophrenia spectrum disorders have heterogeneous outcomes and currently no marker
predicts the course of illness. Motor abnormalities (MAs) are inherent to psychosis, the risk of …

Motor dysfunction as research domain in the period preceding manifest schizophrenia: a systematic review

D Hirjak, A Meyer-Lindenberg, KM Kubera… - Neuroscience & …, 2018 - Elsevier
Schizophrenia is a severe behavioral syndrome of neurodevelopmental nature marked by
primary or genuine motor abnormalities (GMA), which refer to spontaneous and medication …

Motor dysfunction as research domain across bipolar, obsessive-compulsive and neurodevelopmental disorders

D Hirjak, A Meyer-Lindenberg, S Fritze… - Neuroscience & …, 2018 - Elsevier
Although genuine motor abnormalities (GMA) are frequently found in schizophrenia, they
are also considered as an intrinsic feature of bipolar, obsessive-compulsive, and …

Altered task modulation of global signal topography in the default-mode network of unmedicated major depressive disorder

X Lu, J Zhang, F Gu, H Zhang, M Zhang, R Song… - Journal of affective …, 2022 - Elsevier
Background Altered global signal (GS) topography features in the resting-state fMRI of major
depressive disorder (MDD), showing abnormally strong global signal representation in the …

Cerebellar stimulation in schizophrenia: a systematic review of the evidence and an overview of the methods

JPY Hua, SV Abram, JM Ford - Frontiers in Psychiatry, 2022 - frontiersin.org
Background Cerebellar structural and functional abnormalities underlie widespread deficits
in clinical, cognitive, and motor functioning that are observed in schizophrenia …

Patterns of co‐altered brain structure and function underlying neurological soft signs in schizophrenia spectrum disorders

D Hirjak, M Rashidi, S Fritze, AL Bertolino… - Human Brain …, 2019 - Wiley Online Library
Neurological soft signs (NSS) comprise a broad range of subtle neurological deficits and are
considered to represent external markers of sensorimotor dysfunction frequently found in …

The behavioral mapping of psychomotor slowing in psychosis demonstrates heterogeneity among patients suggesting distinct pathobiology

N Nadesalingam, S Lefebvre, D Alexaki… - Schizophrenia …, 2023 - academic.oup.com
Objectives Psychomotor slowing (PS) occurs in up to half of schizophrenia patients and is
linked to poorer outcomes. As standard treatment fails to improve PS, novel approaches are …

Progress in sensorimotor neuroscience of schizophrenia spectrum disorders: Lessons learned and future directions

D Hirjak, A Meyer-Lindenberg, F Sambataro… - Progress in Neuro …, 2021 - Elsevier
The number of neuroimaging studies on movement disorders, sensorimotor, and
psychomotor functioning in schizophrenia spectrum disorders (SSD) has steadily increased …

Sensorimotor neuroscience in mental disorders: progress, perspectives and challenges

D Hirjak, A Meyer-Lindenberg, F Sambataro… - Schizophrenia …, 2021 - academic.oup.com
The research in the field of sensorimotor functioning 1–4 in distinct psychiatric disorders has
grown exponentially in the last 3 decades (see also recent reviews 2, 4–9), spurring a …