Effect of early sustained prophylactic hypothermia on neurologic outcomes among patients with severe traumatic brain injury: the POLAR randomized clinical trial

DJ Cooper, AD Nichol, M Bailey, S Bernard… - Jama, 2018 - jamanetwork.com
Importance After severe traumatic brain injury, induction of prophylactic hypothermia has
been suggested to be neuroprotective and improve long-term neurologic outcomes …

Temperature management in the ICU

A Drewry, NM Mohr - Critical care medicine, 2022 - journals.lww.com
OBJECTIVE: Temperature abnormalities are recognized as a marker of human disease, and
the therapeutic value of temperature is an attractive treatment target. The objective of this …

Cerebral edema in traumatic brain injury: a historical framework for current therapy

BE Zusman, PM Kochanek, RM Jha - Current treatment options in …, 2020 - Springer
Purpose of review The purposes of this narrative review are to (1) summarize a
contemporary view of cerebral edema pathophysiology,(2) present a synopsis of current …

Systemic antibiotic prophylaxis does not affect infectious complications in pediatric burn injury: A meta-analysis

A Csenkey, G Jozsa, N Gede, E Pakai, B Tinusz… - PLoS …, 2019 - journals.plos.org
In pediatric burns the use of systemic antibiotic prophylaxis is a standard procedure in some
burn centers, though its beneficial effect on the infectious complications is debated. The …

The effectiveness of early prophylactic hypothermia in adult patients with traumatic brain injury: A systematic review and meta-analysis

X Wu, Y Tao, L Marsons, P Dee, D Yu, Y Guan… - Australian Critical …, 2021 - Elsevier
Objectives Previously published systematic reviews have explored the effects of therapeutic
hypothermia on adult patients with traumatic brain injury (TBI). However, none explored the …

Menthol can be safely applied to improve thermal perception during physical exercise: a meta-analysis of randomized controlled trials

P Keringer, N Farkas, N Gede, P Hegyi, Z Rumbus… - Scientific reports, 2020 - nature.com
Menthol is often used as a cold-mimicking substance to allegedly enhance performance
during physical activity, however menthol-induced activation of cold-defence responses …

Effect of hypothermia in the emergency department on the outcome of trauma patients: a cross-sectional analysis

TM Hsieh, PJ Kuo, SY Hsu, PC Chien… - International Journal of …, 2018 - mdpi.com
This study aimed to assess whether hypothermia is an independent predictor of mortality in
trauma patients in the condition of defining hypothermia as body temperatures of< 36° C …

Hypothermia for patients requiring evacuation of subdural hematoma: a multicenter randomized clinical trial

GW Hergenroeder, S Yokobori, HA Choi, K Schmitt… - Neurocritical care, 2022 - Springer
Background Hypothermia is neuroprotective in some ischemia–reperfusion injuries.
Ischemia–reperfusion injury may occur with traumatic subdural hematoma (SDH). This study …

Overview of hypothermia, its role in neuroprotection, and the application of prophylactic hypothermia in traumatic brain injury

C Trieu, S Rajagopalan, WA Kofke… - Anesthesia & …, 2023 - journals.lww.com
The current standard of practice is to maintain normothermia in traumatic brain injury (TBI)
patients despite the theoretical benefits of hypothermia and numerous animal studies with …

Dietary supplementation of transient receptor potential vanilloid-1 channel agonists reduces serum total cholesterol level: a meta-analysis of controlled human trials

L Kelava, D Nemeth, P Hegyi, P Keringer… - Critical Reviews in …, 2022 - Taylor & Francis
Abnormal cholesterol level is a major risk factor in the development of atherosclerosis, which
is a fundamental derangement in cardiovascular diseases. Any efforts should be undertaken …