Acute myeloid leukaemia

CD DiNardo, HP Erba, SD Freeman, AH Wei - The Lancet, 2023 - thelancet.com
Progress in acute myeloid leukaemia treatment is occurring at an unprecedented pace. The
past decade has witnessed an increasingly improved scientific understanding of the …

Association of measurable residual disease with survival outcomes in patients with acute myeloid leukemia: a systematic review and meta-analysis

NJ Short, S Zhou, C Fu, DA Berry, RB Walter… - JAMA …, 2020 - jamanetwork.com
Importance Measurable residual disease (MRD) refers to neoplastic cells that cannot be
detected by standard cytomorphologic analysis. In patients with acute myeloid leukemia …

Indications for haematopoietic cell transplantation for haematological diseases, solid tumours and immune disorders: current practice in Europe, 2022

JA Snowden, I Sánchez-Ortega… - Bone marrow …, 2022 - nature.com
For over two decades, the EBMT has updated recommendations on indications for
haematopoietic cell transplantation (HCT) practice based on clinical and scientific …

2021 Update on MRD in acute myeloid leukemia: a consensus document from the European LeukemiaNet MRD Working Party

M Heuser, SD Freeman… - Blood, The Journal …, 2021 - ashpublications.org
Measurable residual disease (MRD) is an important biomarker in acute myeloid leukemia
(AML) that is used for prognostic, predictive, monitoring, and efficacy-response …

Diagnosis and management of AML in adults: 2022 recommendations from an international expert panel on behalf of the ELN

H Döhner, AH Wei, FR Appelbaum… - Blood, The Journal …, 2022 - ashpublications.org
The 2010 and 2017 editions of the European LeukemiaNet (ELN) recommendations for
diagnosis and management of acute myeloid leukemia (AML) in adults are widely …

Acute myeloid leukaemia in adult patients: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

M Heuser, Y Ofran, N Boissel, SB Mauri… - Annals of …, 2020 - annalsofoncology.org
Acute myeloid leukaemia (AML) incidence is age dependent, rising markedly in patients
aged! 60 years. Ageing of the European population may therefore contribute to the reported …

T cell receptor gene therapy targeting WT1 prevents acute myeloid leukemia relapse post-transplant

AG Chapuis, DN Egan, M Bar, TM Schmitt… - Nature medicine, 2019 - nature.com
Relapse after allogeneic hematopoietic cell transplantation (HCT) is the leading cause of
death in patients with acute myeloid leukemia (AML) entering HCT with poor-risk features …

Consensus proposal for revised International Working Group 2023 response criteria for higher-risk myelodysplastic syndromes

AM Zeidan, U Platzbecker… - Blood, The Journal …, 2023 - ashpublications.org
Myelodysplastic syndromes/myelodysplastic neoplasms (MDS) are associated with variable
clinical presentations and outcomes. The initial response criteria developed by the …

Augmented reduced-intensity regimen does not improve postallogeneic transplant outcomes in acute myeloid leukemia

C Craddock, A Jackson, J Loke, S Siddique… - Journal of Clinical …, 2021 - ascopubs.org
PURPOSE Reduced-intensity conditioning (RIC) regimens have extended the curative
potential of allogeneic stem-cell transplantation to older adults with high-risk acute myeloid …

Acute myeloid leukemia: 2019 update on risk‐stratification and management

EH Estey - American journal of hematology, 2018 - Wiley Online Library
Outcome in patients with acute myeloid leukemia (AML) ranges from death within a few days
of beginning treatment (treatment related mortality, TRM) to likely cure. The major reason …